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WormBase Tree Display for Gene: WBGene00000534

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Name Class

WBGene00000534SMapS_parentSequenceR01B10
IdentityVersion2
NameCGC_namecpi-2Paper_evidenceWBPaper00026724
WBPaper00005846
WBPaper00024997
Person_evidenceWBPerson4368
WBPerson390
Sequence_nameR01B10.1
Molecular_nameR01B10.1a
R01B10.1a.1
CE25962
R01B10.1b
Other_namecli-1
CELE_R01B10.1Accession_evidenceNDBBX284605
Public_namecpi-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
204 Jan 2006 11:04:12WBPerson2970Name_changeCGC_namecpi-2
Other_namecli-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcpi
AlleleWBVar00210049
WBVar00092502
WBVar01499528
WBVar01499173
WBVar01499174
WBVar01499740
WBVar01500129
WBVar00310175
WBVar00459692
WBVar00459693
WBVar00459694
WBVar00459695
WBVar01740410
WBVar00598901
WBVar02124237
WBVar01499496
WBVar01016008
WBVar01499316
WBVar01016009
WBVar01016010
WBVar01016011
WBVar01973713
WBVar01016012
WBVar01016013
WBVar01016014
WBVar01016015
WBVar01016016
WBVar01651823
WBVar02122250
WBVar01500066
StrainWBStrain00031908
WBStrain00054915
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (48)
ParalogWBGene00000535Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00016523Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00023486Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionAutomated_descriptionEnables cysteine-type endopeptidase inhibitor activity. Involved in positive regulation of vitellogenesis; regulation of oocyte development; and regulation of protein processing. Located in extracellular space and yolk granule. Expressed in hypodermis; pharyngeal gland cell; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; CST3-related cerebral amyloid angiopathy; artery disease (multiple); and autoimmune disease of the nervous system (multiple). Is an ortholog of several human genes including CST1 (cystatin SN); CST2 (cystatin SA); and CST3 (cystatin C).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (17)
Molecular_infoCorresponding_CDSR01B10.1a
Corresponding_transcriptR01B10.1b
R01B10.1a.1
Other_sequence (85)
Associated_featureWBsf028073
WBsf646851
WBsf655095
WBsf661303
WBsf661304
WBsf661305
WBsf1000163
WBsf231832
Experimental_infoRNAi_result (11)
Expr_patternExpr3711
Expr7868
Expr7869
Expr1020802
Expr1030320
Expr1154795
Expr2010490
Expr2028730
Drives_constructWBCnstr00012962
Construct_productWBCnstr00012962
AntibodyWBAntibody00001122
Microarray_results (31)
Expression_cluster (137)
InteractionWBInteraction000143932
WBInteraction000306622
WBInteraction000552020
WBInteraction000577508
Map_infoMapVPosition-0.400385Error0.008156
PositivePositive_cloneR01B10Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4964
4240
Pseudo_map_position
Reference (12)
RemarkSequence connection from [Hashmi S, Lustigan S], [krb 020711]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene