WormBase Tree Display for Gene: WBGene00000529

WBGene00000529 SMap: S_parent: Sequence: CHROMOSOME_II
  Identity: Version: 1
    Name: CGC_name: clh-2
      Sequence_name: B0491.8
      Molecular_name: B0491.8a
        B0491.8a.1
        CE53983
        B0491.8b
        CE27790
        B0491.8c
        CE02153
        B0491.8b.1
        B0491.8c.1
      Other_name: ceclc-2 Accession_evidence: EMBL AF173171
        clc-2
        CELE_B0491.8 Accession_evidence: NDB BX284602
      Public_name: clh-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: clh
    Allele: WBVar00378244
      WBVar00768547
      WBVar00378245
      WBVar00768548
      WBVar00378246
      WBVar00768549
      WBVar01499702
      WBVar00768550
      WBVar00378247
      WBVar00378248
      WBVar00768551
      WBVar00768552
      WBVar00378249
      WBVar00378250
      WBVar00768553
      WBVar00378251
      WBVar00768554
      WBVar00768555
      WBVar00255422
      WBVar00378252
      WBVar00768556
      WBVar00378253
      WBVar01497132
      WBVar00768557
      WBVar00378254
      WBVar00768558
      WBVar00378255
      WBVar00768559
      WBVar00378256
      WBVar00378257
      WBVar00768560
      WBVar00768561
      WBVar02040547
      WBVar00768562
      WBVar00768563
      WBVar00768564
      WBVar01498613
      WBVar00768565
      WBVar00768566
      WBVar00768567
      WBVar00768568
      WBVar01311796
      WBVar00768569
      WBVar01311800
      WBVar00768570
      WBVar01498435
      WBVar01547041
      WBVar00768571
      WBVar01311801
      WBVar00768572
      WBVar01547042
      WBVar01311802
      WBVar00768573
      WBVar01547043
      WBVar01311803
      WBVar01547044
      WBVar01311804
      WBVar00768574
      WBVar01311805
      WBVar00768575
      WBVar01547045
      WBVar01547046
      WBVar00768576
      WBVar01405681
      WBVar00768577
      WBVar01478017
      WBVar01547047
      WBVar01311808
      WBVar01478018
      WBVar00768578
      WBVar01311809
      WBVar01547048
      WBVar01311810
      WBVar00768579
      WBVar01547049
      WBVar01311812
      WBVar01376684
      WBVar00242869
      WBVar00768580
      WBVar01311813
      WBVar00242870
      WBVar01439940
      WBVar00768581
      WBVar01311814
      WBVar00242871
      WBVar01439941
      WBVar00768582
      WBVar00768583
      WBVar01439943
      WBVar01538680
      WBVar01311815
      WBVar00768584
      WBVar01439945
      WBVar01311816
      WBVar01311817
      WBVar00768585
      WBVar01439947
      WBVar00768586
      WBVar01439949
      WBVar01311819
      WBVar01311820
      WBVar00768587
      WBVar00768588
      WBVar01311821
      WBVar00768589
      WBVar00768590
      WBVar00768591
      WBVar00768592
      WBVar00768593
      WBVar00768594
      WBVar00768595
      WBVar00768596
      WBVar00768597
      WBVar00768598
      WBVar00768599
      WBVar00768600
      WBVar00768601
      WBVar00768602
      WBVar01400364
      WBVar01400365
      WBVar00263574
      WBVar01244759
      WBVar01244761
      WBVar01244763
      WBVar01244766
      WBVar01499766
      WBVar01792286
      WBVar01993982
      WBVar01993983
      WBVar02108157
      WBVar02068260
      WBVar02070682
      WBVar01255006
      WBVar01605044
      WBVar01605045
      WBVar02052349
      WBVar00249416
      WBVar01605046
      WBVar01605047
      WBVar01943594
      WBVar01943595
      WBVar01943596
      WBVar00142713
      WBVar01960284
      WBVar02014339
      WBVar01784542
      WBVar01784543
      WBVar01784544
      WBVar00269043
      WBVar00229545
      WBVar00229548
      WBVar01935640
      WBVar00229551
      WBVar00229552
      WBVar00768480
      WBVar00768481
      WBVar00768482
      WBVar00768483
      WBVar00768484
      WBVar00768485
      WBVar01895436
      WBVar00768486
      WBVar01895437
      WBVar00238665
      WBVar00768487
      WBVar01895438
      WBVar00175802
      WBVar01895439
      WBVar00768488
      WBVar00768489
      WBVar00175803
      WBVar01895440
      WBVar00768490
      WBVar00175804
      WBVar00768491
      WBVar00175805
      WBVar00175806
      WBVar00768492
      WBVar00175807
      WBVar00091920
      WBVar00768493
      WBVar00175808
      WBVar00768494
      WBVar00175809
      WBVar00768495
      WBVar00175810
      WBVar00768496
      WBVar00175811
      WBVar00768497
      WBVar00768498
      WBVar00768499
      WBVar00768500
      WBVar00768501
      WBVar01413927
      WBVar00768502
      WBVar00768503
      WBVar00553033
      WBVar00768504
      WBVar00768505
      WBVar00768506
      WBVar00768507
      WBVar00768508
      WBVar00768509
      WBVar00768510
      WBVar00768511
      WBVar02033577
      WBVar02033579
      WBVar00768512
      WBVar00768513
      WBVar02033580
      WBVar02033581
      WBVar00768514
      WBVar00768515
      WBVar00768516
      WBVar00599464
      WBVar00768517
      WBVar00599465
      WBVar00768518
      WBVar00599466
      WBVar00599467
      WBVar00260173
      WBVar00768519
      WBVar00768520
      WBVar00768521
      WBVar00768522
      WBVar01379823
      WBVar02084874
      WBVar00768523
      WBVar01498941
      WBVar00768524
      WBVar01379834
      WBVar00768525
      WBVar00768526
      WBVar00768527
      WBVar01379845
      WBVar00378225
      WBVar00768528
      WBVar00378226
      WBVar00768529
      WBVar02035911
      WBVar00768530
      WBVar00378227
      WBVar00378228
      WBVar00768531
      WBVar00768532
      WBVar00378229
      WBVar00768533
      WBVar00378230
      WBVar00378231
      WBVar00768534
      WBVar02130724
      WBVar00768535
      WBVar00378232
      WBVar02130725
      WBVar00768536
      WBVar00378233
      WBVar00378234
      WBVar00768537
      WBVar02130726
      WBVar00378235
      WBVar00768538
      WBVar00378236
      WBVar00768539
      WBVar00378237
      WBVar00768540
      WBVar00768541
      WBVar00378238
      WBVar01642070
      WBVar00768542
      WBVar00378239
      WBVar00768543
      WBVar00378240
      WBVar00768544
      WBVar00378241
      WBVar00768545
      WBVar00378242
      WBVar00378243
      WBVar02146128
      WBVar00768546
    Strain: WBStrain00031534
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (45)
    Paralog: WBGene00000528 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000530 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000531 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000532 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000533 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: clh-2 encodes a chloride channel protein that is required for embryonic viability; may have two transcripts transcribed from alternative promoters, and the two transcripts might be expressed in different cell types. Paper_evidence: WBPaper00003797
            WBPaper00004423
            WBPaper00004651
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable voltage-gated chloride channel activity. Predicted to be involved in chloride transport. Predicted to be located in plasma membrane. Expressed in several structures, including ganglia; intestine; pharyngeal-intestinal valve; somatic nervous system; and vulval muscle. Human ortholog(s) of this gene implicated in Thomsen disease; idiopathic generalized epilepsy 11; and primary hyperaldosteronism. Is an ortholog of human CLCN1 (chloride voltage-gated channel 1) and CLCN2 (chloride voltage-gated channel 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:446 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2020)
      DOID:0081336 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2019)
      DOID:2106 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2019)
      DOID:0111312 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2020)
  Molecular_info: Corresponding_CDS: B0491.8a
      B0491.8b
      B0491.8c
    Corresponding_CDS_history: B0491.8a:wp274
    Corresponding_transcript: B0491.8a.1
      B0491.8b.1
      B0491.8c.1
    Other_sequence (26)
    Associated_feature (12)
  Experimental_info: RNAi_result: WBRNAi00011514 Inferred_automatically: RNAi_primary
      WBRNAi00000398 Inferred_automatically: RNAi_primary
      WBRNAi00077547 Inferred_automatically: RNAi_primary
      WBRNAi00039107 Inferred_automatically: RNAi_primary
      WBRNAi00009806 Inferred_automatically: RNAi_primary
      WBRNAi00039106 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1122
      Expr1123
      Expr1188
      Expr1024352
      Expr1030316
      Expr1143264
      Expr2010229
      Expr2028471
    Drives_construct: WBCnstr00010090
      WBCnstr00010091
      WBCnstr00010139
      WBCnstr00037470
    Construct_product: WBCnstr00037470
    Microarray_results (36)
    Expression_cluster (154)
    Interaction: WBInteraction000133971
      WBInteraction000133972
      WBInteraction000135502
      WBInteraction000135503
      WBInteraction000138010
  Map_info: Map: II Position: 3.45766 Error: 0.002945
    Positive: Positive_clone: B0491 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: sequence connection from [George AL]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene