WormBase Tree Display for Gene: WBGene00000497
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| WBGene00000497 | SMap | S_parent | Sequence | F48A11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | chs-2 | Person_evidence | WBPerson50 | |||||
| Sequence_name | F48A11.1 | ||||||||
| Molecular_name | F48A11.1a | ||||||||
| F48A11.1a.1 | |||||||||
| CE39155 | |||||||||
| F48A11.1b | |||||||||
| CE50690 | |||||||||
| F48A11.1c | |||||||||
| CE50769 | |||||||||
| F48A11.1b.1 | |||||||||
| F48A11.1c.1 | |||||||||
| Other_name | chs-1 | ||||||||
| chi-2 | CGC_data_submission | ||||||||
| CELE_F48A11.1 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | chs-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 05 Jul 2004 10:24:20 | WBPerson1971 | Name_change | CGC_name | chs-2 | ||||
| 3 | 30 Apr 2015 13:34:49 | WBPerson1983 | Event | Acquires_merge | WBGene00018583 | ||||
| Acquires_merge | WBGene00018583 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | chs | ||||||||
| Allele (220) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (47) | |||||||||
| Paralog | WBGene00000496 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Concise_description | chs-2 encodes a putative chitin synthase, paralogous to CHS-1; CHS-2 isrequired for synthesis of chitin lining the inner pharyngeal surface(primarily in the buccal cavity and grinder), while CHS-1 is dispensablefor pharyngeal chitin; CHS-2 is also required for normal pharyngealshape and function, and for larval viability; chs-2(RNAi) animals haveabnormally large, misshapen grinders, and arrest as early larvae; chs-2is expressed by the glandular pharyngeal g1 and g2 cells, and by m3 andm4 myoepithelial cells; chs-2 is transcribed in short periods beforeeach larval molt; the pharyngeal expression of chs-2 parallels gna-1;CHS-2 is predicted to be in the plasma membrane rather than the Golgiapparatus. | Paper_evidence | WBPaper00004881 | |||||
| WBPaper00006390 | |||||||||
| WBPaper00012846 | |||||||||
| WBPaper00026721 | |||||||||
| WBPaper00028588 | |||||||||
| WBPaper00029233 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 07 Apr 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable chitin synthase activity. Involved in chitin biosynthetic process and positive regulation of nematode larval development. Predicted to be located in cell periphery and cell septum. Expressed in pharynx. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F48A11.1a | |||||||
| F48A11.1b | |||||||||
| F48A11.1c | |||||||||
| Corresponding_CDS_history | F48A11.1:wp149 | ||||||||
| Corresponding_transcript | F48A11.1a.1 | ||||||||
| F48A11.1b.1 | |||||||||
| F48A11.1c.1 | |||||||||
| Other_sequence (17) | |||||||||
| Associated_feature (17) | |||||||||
| Experimental_info | RNAi_result (14) | ||||||||
| Expr_pattern | Expr3654 | ||||||||
| Expr11043 | |||||||||
| Expr1021151 | |||||||||
| Expr1024170 | |||||||||
| Expr1030293 | |||||||||
| Expr1151543 | |||||||||
| Expr1151544 | |||||||||
| Expr2010000 | |||||||||
| Expr2028241 | |||||||||
| Drives_construct | WBCnstr00009128 | ||||||||
| WBCnstr00011575 | |||||||||
| WBCnstr00017872 | |||||||||
| WBCnstr00023060 | |||||||||
| Microarray_results (48) | |||||||||
| Expression_cluster (181) | |||||||||
| Interaction | WBInteraction000241924 | ||||||||
| WBInteraction000463268 | |||||||||
| Map_info | Map | II | Position | -15.8229 | Error | 0.018071 | |||
| Positive | Positive_clone | F48A11 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (12) | |||||||||
| Remark | Gene was renamed from chi-2 to chs-2 at request of CGC, note that the other name 'chs-1' is from the Brugia malayi ortholog...this ortholog may be renamed in the future to clarify the situation. | CGC_data_submission | |||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
