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WormBase Tree Display for Gene: WBGene00000496

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Name Class

WBGene00000496SMapS_parentSequenceT25G3
IdentityVersion2
NameCGC_namechs-1Person_evidenceWBPerson50
Sequence_nameT25G3.2
Molecular_nameT25G3.2
T25G3.2.1
CE39183
T25G3.2.2
Other_namechi-1CGC_data_submission
chs-2
CELE_T25G3.2Accession_evidenceNDBBX284601
Public_namechs-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
205 Jul 2004 10:20:16WBPerson1971Name_changeCGC_namechs-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classchs
Allele (57)
StrainWBStrain00031890
RNASeq_FPKM (74)
GO_annotation (26)
Contained_in_operonCEOP1400
Ortholog (42)
ParalogWBGene00000497Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionchs-1 encodes a chitin synthase, paralogous to CHS-2; chs-1 is requiredfor embryonic chitin synthesis, eggshell synthesis and osmoticintegrity, error-free chromosomal segregation during meiosis, polar bodyextrusion, association of the sperm pronucleus/centrosome complex (SPCC)with the early embryonic cortex, localization of PAR-2 in early embryos,posterior localization of P granules or PIE-1, and pseudocleavage; CHS-1is also, independently of chitin synthesis, required for normallocalization of MBK-2 to cortex and punctae in early embryos; CHS-1 isdispensable for synthesis of pharyngeal cuticle, since chs-1(ok1120)mutants have it normally; CHS-1 localizes to the oocyte plasma membrane and .cell cortexPaper_evidenceWBPaper00004881
WBPaper00006390
WBPaper00012846
WBPaper00026721
WBPaper00028588
WBPaper00029233
WBPaper00031014
WBPaper00035426
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated16 Nov 2010 00:00:00
Automated_descriptionPredicted to enable chitin synthase activity. Involved in cell wall chitin biosynthetic process; eggshell formation; and positive regulation of protein localization to cell cortex. Located in cell cortex and plasma membrane. Expressed in Psub1.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST25G3.2
Corresponding_CDS_historyT25G3.2:wp149
Corresponding_transcriptT25G3.2.1
T25G3.2.2
Other_sequence (54)
Associated_featureWBsf643461
WBsf643462
WBsf656537
WBsf656538
WBsf218023
WBsf218024
Experimental_infoRNAi_result (17)
Expr_patternExpr3655
Expr4906
Expr11042
Expr14401
Expr1011456
Expr1030292
Expr1157706
Expr2009999
Expr2028240
Drives_constructWBCnstr00011576
WBCnstr00037497
Construct_productWBCnstr00001287
WBCnstr00019030
WBCnstr00037497
Microarray_results (19)
Expression_cluster (168)
Interaction (188)
Map_infoMapIPosition2.13842Error0.012536
PositivePositive_cloneT25G3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4887
5298
Pseudo_map_position
Reference (23)
RemarkGene was renamed from chi-1 to chs-1 at request of CGC, note that the other name 'chs-2' is from the Brugia malayi ortholog...this ortholog may be renamed in the future to clarify the situation.CGC_data_submission
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene