| WBGene00000484 | Evidence | CGC_data_submission |
|---|
| SMap | S_parent | Sequence | F38G1 |
| Identity | Version | 1 |
| | Name | CGC_name | che-2 | Person_evidence | WBPerson261 |
| | | Sequence_name | F38G1.1 |
| | | Molecular_name | F38G1.1 |
| | | | F38G1.1.1 |
| | | | CE25876 |
| | | Other_name | CELE_F38G1.1 | Accession_evidence | NDB | BX284606 |
| | | Public_name | che-2 |
| | DB_info | Database (12) |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | che |
| | Reference_allele | WBVar00143695 |
| | Allele (93) |
| | Legacy_information | e1033 : non-chemotactic to sodium ion slightly small defective osmotic avoidance defective dauer formation males impotent; no FITC uptake; ciliated neurons have abnormal stunted ultrastructure. ES2 ME0. NA1. |
| | | See also e1033 |
| | | [C.elegansII] e1033 : non-chemotactic to sodium ion; slightly small; defective osmotic avoidance; defective dauer formation; males impotent; Dyf (no FITC uptake); ciliated neurons have abnormal stunted ultrastructure. ES2. ME0.OA5: m127, mn330mut, mn395 etc. [Lewis and Hodgkin 1977; Starich et al. 1995; DR; SP; NJ] |
| | Strain | WBStrain00030520 |
| | | WBStrain00030521 |
| | | WBStrain00004231 |
| | | WBStrain00006208 |
| | RNASeq_FPKM (74) |
| | GO_annotation (19) |
| | Ortholog (39) |
| | Structured_description | Concise_description | che-2 encodes a protein that contains G-protein beta-like WD-40 repeats that affects chemotaxis, dauer formation, and longevity; expressed in the cilia of most ciliated sensory neurons, some head neurons, and male tail rays. | Paper_evidence | WBPaper00001482 |
| | | | | | WBPaper00001786 |
| | | | | | WBPaper00002033 |
| | | | | | WBPaper00003761 |
| | | | | | WBPaper00003977 |
| | | | | | WBPaper00004692 |
| | | | | | WBPaper00005596 |
| | | | | Curator_confirmed | WBPerson48 |
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | Automated_description | Involved in several processes, including dauer larval development; negative regulation of transforming growth factor beta receptor signaling pathway; and positive regulation of locomotion involved in locomotory behavior. Located in ciliary basal body and non-motile cilium. Expressed in neurons. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 2. Is an ortholog of human IFT80 (intraflagellar transport 80). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Disease_info | Potential_model | DOID:0110086 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29262) |
| Molecular_info | Corresponding_CDS | F38G1.1 |
| | Corresponding_transcript | F38G1.1.1 |
| | Other_sequence | Acan_isotig12713 |
| | | JI226764.1 |
| | Associated_feature | WBsf042305 |
| | | WBsf647785 |
| | | WBsf1003791 |
| | | WBsf235268 |
| Experimental_info | RNAi_result | WBRNAi00014580 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00068042 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00067404 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00067940 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00046733 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr1157 |
| | | Expr10123 |
| | | Expr1024294 |
| | | Expr1030285 |
| | | Expr1150609 |
| | | Expr2009965 |
| | | Expr2028205 |
| | Drives_construct (17) |
| | Construct_product (11) |
| | Microarray_results (20) |
| | Expression_cluster | WBPaper00032031:DConiospora_downregulated_OligoArray_24h |
| | | WBPaper00033065:cyc-1(RNAi)_downregulated |
| | | WBPaper00037950:A-class-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:all-neurons_L1-larva_expressed |
| | | WBPaper00037950:all-neurons_L2-larva_expressed |
| | | WBPaper00037950:all-neurons_larva_enriched |
| | | WBPaper00037950:all-neurons_larva_SelectivelyEnriched |
| | | WBPaper00037950:AVA-neuron_L1-larva_expressed |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00037950:BAG-neuron_embryo_enriched |
| | | WBPaper00037950:BAG-neuron_embryo_SelectivelyEnriched |
| | | WBPaper00037950:bodywall-muscle_L1-larva_expressed |
| | | WBPaper00037950:coelomocytes_L2-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_CoreEnriched |
| | | WBPaper00037950:dopaminergic-neurons_embryo_enriched |
| | | WBPaper00037950:dopaminergic-neurons_embryo_SelectivelyEnriched |
| | | WBPaper00037950:dopaminergic-neurons_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_larva_enriched |
| | | WBPaper00037950:dopaminergic-neurons_larva_SelectivelyEnriched |
| | | WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed |
| | | WBPaper00037950:hypodermis_L1-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq |
| | | WBPaper00045390:tunicamycin_downregulated |
| | | WBPaper00045390:ubc-9(RNAi)_downregulated |
| | | WBPaper00048923:Aging_regulated |
| | | WBPaper00048988:neuron_enriched |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00050231:male_enriched |
| | | WBPaper00050344:ASER-neuron_enriched |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C |
| | | WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C |
| | | WBPaper00050726:OsmoticStress_regulated_Food |
| | | WBPaper00050726:OsmoticStress_regulated_NoFood |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00053295:lin-22(icb38)_upregulated |
| | | WBPaper00053295:lin-22(ot269)_upregulated |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053771:up_at_dpy-7(e88) |
| | | WBPaper00054493:hpl-2(tm1489)_upregulated |
| | | WBPaper00054758:alg-1(gk204)_upregulated |
| | | WBPaper00055226:ADR-2_target_N2 |
| | | WBPaper00055354:eat-2(ad1116)_upregulated |
| | | WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin_upregulated |
| | | WBPaper00055354:Rifampicin-Psora_upregulated |
| | | WBPaper00055354:Rifampicin_upregulated |
| | | WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047) |
| | | WBPaper00056090:E.faecalis_upregulated_N2 |
| | | WBPaper00056169:rrf-3(pk1426)_upregulated_embryo |
| | | WBPaper00056284:ints-11(RNAi)_downregulated |
| | | WBPaper00056443:sek-1(km4)_upregulated |
| | | WBPaper00057041:unc-70(cas983)_downregulated |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058598:spn-4(tm291)_upregulated |
| | | WBPaper00058691:set-2(bn129)_upregulated |
| | | WBPaper00058948:PA14_downregulated |
| | | WBPaper00059117:B.subtilis_upregulated |
| | | WBPaper00059231:alh-6(lax105)_L4_upregulated |
| | | WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA |
| | | WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated |
| | | WBPaper00059421:daf-3(mgDf90)_downregulated |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00060014:set-2(tm1630)_downregulated |
| | | WBPaper00060014:set-2(zr2012)_downregulated |
| | | WBPaper00060526:plp-1(ok2155)_downregulated |
| | | WBPaper00060661:sensory-neuron_enriched |
| | | WBPaper00060811:L1_vs_adult_upregulated_neural |
| | | WBPaper00060909:atfs-1(et18)_downregulated |
| | | WBPaper00060911:prx-5(RNAi)_upregulated_mRNA |
| | | WBPaper00061081:E.faecalis_upregulated_N2 |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061340:ADE |
| | | WBPaper00061340:ADF |
| | | WBPaper00061340:ADF_AWB |
| | | WBPaper00061340:ASE |
| | | WBPaper00061340:ASG |
| | | WBPaper00061340:ASG_AWA |
| | | WBPaper00061340:ASI_parent |
| | | WBPaper00061340:ASJ |
| | | WBPaper00061340:ASK |
| | | WBPaper00061340:ASK_parent |
| | | WBPaper00061340:AUA |
| | | WBPaper00061340:AWB |
| | | WBPaper00061340:AWC |
| | | WBPaper00061340:BAG |
| | | WBPaper00061340:CEP |
| | | WBPaper00061340:IL1 |
| | | WBPaper00061340:IL1_parent |
| | | WBPaper00061340:IL2 |
| | | WBPaper00061340:Neuroblast_ADE_ADA |
| | | WBPaper00061340:Neuroblast_ASJ_AUA |
| | | WBPaper00061340:Neuroblast_HSN_PHB |
| | | WBPaper00061340:Neuroblast_URX_CEPDx |
| | | WBPaper00061340:OLL_parent |
| | | WBPaper00061340:OLQ |
| | | WBPaper00061340:OLQ_parent |
| | | WBPaper00061340:URX |
| | | WBPaper00061341:28C_24h_upregulated |
| | | WBPaper00061341:28C_48h_upregulated |
| | | WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection |
| | | WBPaper00061527:rab-28-jbts-14_9542 |
| | | WBPaper00061853:osm-3(dh441)_downregulated |
| | | WBPaper00061995:mter-4(syb3662syb3403)_downregulated |
| | | WBPaper00062056:efl-1(se1)_upregulated |
| | | WBPaper00062103:neuron_enriched |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062325:muscle_depleted_coding-RNA |
| | | WBPaper00062446:nhr-8(hd117)_upregulated |
| | | WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium |
| | | WBPaper00064306:Agaro-oligosaccharides_upregulated |
| | | WBPaper00064721:fasn-1(g14)_downregulated_starved |
| | | WBPaper00065096:25C_vs_20C_downregulated |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065158:AFD_enriched |
| | | WBPaper00065581:hpk-1(pk1393)_upregulated |
| | | WBPaper00065749:endu-2(tm4977)_upregulated |
| | | WBPaper00065841:25_0 |
| | | WBPaper00065841:25_1 |
| | | WBPaper00065841:36_2 |
| | | WBPaper00065841:36_3 |
| | | WBPaper00065841:39_0 |
| | | WBPaper00065841:39_1 |
| | | WBPaper00065841:39_2 |
| | | WBPaper00065841:39_3 |
| | | WBPaper00065841:44_1 |
| | | WBPaper00065841:47_0 |
| | | WBPaper00065841:100_0 |
| | | WBPaper00066110:tetraploid_vs_diploid_upregulated |
| | | cgc4489_group_13 |
| | | WBPaper00024671:AFD_AWB_vs_unsorted_upregulated |
| | | WBPaper00030839:Embryo_Pan_Neuronal |
| | | WBPaper00030839:Larval_Pan_Neuronal |
| | | WBPaper00030985:Enterococcus_faecalis_upregulated |
| | | WBPaper00031532:Larva_Pan_Neuronal_Enriched |
| | | WBPaper00036130:mir-243_up_regulated |
| | | WBPaper00039866:ClassComp_daf-19_downregulated |
| | | WBPaper00039866:SAM_daf-19_downregulated |
| | | WBPaper00040210:Diazinon_24C_regulated |
| | | WBPaper00045673:colistin_upregulated |
| | | WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated |
| | | WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo |
| | | WBPaper00053550:daf-19(m86)_downregulated_L1 |
| | | WBPaper00056330:mrps-5(RNAi)_upregulated |
| | Interaction (81) |
| Map_info | Map | X | Position | -19.7593 | Error | 0.046333 |
| | Well_ordered |
| | Positive | Positive_clone | F38G1 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | 2_point | 3385 |
| | | Multi_point | 1213 |
| | | | 1585 |
| | | | 1856 |
| | | | 2320 |
| | | | 2431 |
| | | | 2432 |
| | | | 4432 |
| | | Pos_neg_data | 5455 |
| | | | 5461 |
| | | | 5466 |
| | | | 5470 |
| | | | 5474 |
| | | | 5478 |
| | | | 5482 |
| | | | 5486 |
| | | | 5490 |
| | | | 5494 |
| Reference (127) |
| Remark | Sequence connection from [Fujiwara M, Katsura I] |
| Method | Gene |
