WormBase Tree Display for Gene: WBGene00000429
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WBGene00000429 | SMap | S_parent | Sequence | C27A12 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | ceh | ||||||
Allele (36) | |||||||
Legacy_information | [C.elegansII] NMK. Encodes homeoprotein. Antibodies stain some pharyngeal cells just before pharyngeal morphogenesis. [Burglin et al. 1989] | ||||||
Strain (11) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (13) | |||||||
Ortholog (42) | |||||||
Paralog | WBGene00018022 | Caenorhabditis elegans | From_analysis | Panther | |||
WBGene00044032 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00012584 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00000432 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00000430 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00022554 | Caenorhabditis elegans | From_analysis | Panther | ||||
Structured_description | Concise_description | ceh-2 encodes a homeodomain protein homologous to Drosophila empty spiracles (EMS) and the vertebrate EMX1 and EMX2 proteins (OMIM:600034, 600035); although the exact biological role of CEH-2 in C. elegans development and/or behavior is not yet known, expression in pharyngeal neurons and muscle, as well as vulval cells (vulB1, vulB2, and vulC) at late stages of development suggests that CEH-2 may play a role in terminal differentiation events in diverse cell types. | Paper_evidence | WBPaper00001190 | |||
WBPaper00011600 | |||||||
WBPaper00013312 | |||||||
WBPaper00022408 | |||||||
Curator_confirmed | WBPerson48 | ||||||
WBPerson1843 | |||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in brain development; neuron differentiation; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in neurons; pharynx; somatic nervous system; and vulva. Human ortholog(s) of this gene implicated in carcinoma (multiple) and stomach cancer. Is an ortholog of human EMX1 (empty spiracles homeobox 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||
DOID:7474 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||
DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||
DOID:10534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||
DOID:4914 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||
DOID:3907 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||
DOID:0050861 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3341) | ||||
Molecular_info | Corresponding_CDS | C27A12.5 | |||||
Corresponding_transcript | C27A12.5.1 | ||||||
Other_sequence (11) | |||||||
Associated_feature | WBsf649210 | ||||||
WBsf664313 | |||||||
WBsf664314 | |||||||
WBsf978314 | |||||||
WBsf983821 | |||||||
WBsf983822 | |||||||
WBsf219523 | |||||||
WBsf219524 | |||||||
WBsf219525 | |||||||
WBsf219526 | |||||||
Transcription_factor | WBTranscriptionFactor000299 | ||||||
Experimental_info | RNAi_result | WBRNAi00029244 | Inferred_automatically | RNAi_primary | |||
WBRNAi00041295 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00003026 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (14) | |||||||
Drives_construct (15) | |||||||
Construct_product | WBCnstr00037547 | ||||||
WBCnstr00041955 | |||||||
Antibody | WBAntibody00000654 | ||||||
Microarray_results (18) | |||||||
Expression_cluster (95) | |||||||
Interaction (100) | |||||||
Map_info | Map | I | Position | 0.702718 | Error | 0.001508 | |
Positive | Positive_clone | C27A12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
NE4 | |||||||
Mapping_data | Multi_point | 4201 | |||||
Pseudo_map_position | |||||||
Reference (30) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |