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WormBase Tree Display for Gene: WBGene00000381

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Name Class

WBGene00000381SMapS_parentSequenceF01F1
IdentityVersion1
NameCGC_namecct-6Person_evidenceWBPerson89
Sequence_nameF01F1.8
Molecular_nameF01F1.8a
F01F1.8a.1
CE01234
F01F1.8b
CE30647
F01F1.8a.2
F01F1.8b.1
Other_nameCELE_F01F1.8Accession_evidenceNDBBX284603
Public_namecct-6
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcct
Allele (24)
Legacy_information[C.elegansII] NMK. Encodes one of 7-9 related subunits of eukaryotic cytosolic chaperonin CCT.Ortholog of mouse Cctz (67% aa sequence identity)[PC]
[C.elegansII] NMK. Encodes one of 7-9 related subunits of eukaryotic cytosolic chaperonin CCT. Ortholog of mouse Cctz (67% aa sequence identity)[PC]
StrainWBStrain00037224
RNASeq_FPKM (74)
GO_annotation (12)
Contained_in_operonCEOP3336
Ortholog (41)
ParalogWBGene00000377Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000378Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000379Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000380Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00020391Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00021934Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00018782Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00002025Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004089Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptioncct-6 encodes, by alternative splicing, two isoforms of a putative zeta subunit of the eukaryotic cytosolic ('T complex') chaperonin, orthologous to human CCT6A (OMIM:104613); CCT-6 represses SKN-1-dependent transcription of gst-4; CCT-6 is expressed in a few cells of pre-comma stage embryos; in mass RNAi assays, CCT-6 is required for normally short life span, and for normal transgene subcellular localization, embryonic and larval viability, fertility, vulval development, locomotion, and osmoregulation.Paper_evidence (14)
Curator_confirmedWBPerson567
WBPerson480
Date_last_updated14 Jan 2008 00:00:00
Automated_descriptionPredicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Predicted to be part of chaperonin-containing T-complex. Is an ortholog of human CCT6B (chaperonin containing TCP1 subunit 6B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF01F1.8a
F01F1.8b
Corresponding_transcriptF01F1.8a.1
F01F1.8a.2
F01F1.8b.1
Other_sequence (166)
Associated_featureWBsf655405
WBsf992556
WBsf226726
WBsf226727
WBsf226728
WBsf226729
Experimental_infoRNAi_result (17)
Expr_patternExpr2045
Expr1011531
Expr1030207
Expr1147738
Expr2009774
Expr2028014
Drives_constructWBCnstr00037582
Construct_productWBCnstr00037582
Microarray_results (27)
Expression_cluster (178)
Interaction (142)
Map_infoMapIIIPosition-1.43903Error5.4e-05
PositivePositive_cloneF01F1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (21)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene