WormBase Tree Display for Gene: WBGene00000288

WBGene00000288 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 1
    Name: CGC_name: cal-4 Person_evidence: WBPerson261
      Sequence_name: T07G12.1
      Molecular_name: T07G12.1a
        T07G12.1a.1
        CE43875
        T07G12.1b
        CE43912
        T07G12.1c
        CE13387
        T07G12.1b.1
        T07G12.1b.2
        T07G12.1c.1
      Other_name: CELE_T07G12.1 Accession_evidence: NDB BX284604
      Public_name: cal-4
    DB_info: Database: AceView gene 4L293
        WormQTL gene WBGene00000288
        WormFlux gene WBGene00000288
        NDB locus_tag CELE_T07G12.1
        Panther gene CAEEL|WormBase=WBGene00000288|UniProtKB=G5EDZ8
          family PTHR23050
        NCBI gene 177945
        RefSeq protein NM_001392392.1
            NM_001392393.1
            NM_001268562.3
        TREEFAM TREEFAM_ID TF354258
        TrEMBL UniProtAcc G5EF93
            G5EDZ8
            O18058
        UniProt_GCRP UniProtAcc G5EDZ8
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cal
    Allele (139)
    RNASeq_FPKM (74)
    GO_annotation: 00015097
      00107176
    Ortholog (31)
    Paralog (18)
    Structured_description: Concise_description: cal-4 encodes one of five predicted C. elegans calcium-binding calmodulin homologs (the others being CAL-1, CAL-2, CAL-3 and CMD-1); as loss of cal-4 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of CAL-4 in C. elegans development and/or behavior is not yet known. Paper_evidence: WBPaper00005654
          Curator_confirmed: WBPerson1843
          Date_last_updated: 18 Oct 2006 00:00:00
      Automated_description: Predicted to enable calcium ion binding activity. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T07G12.1a
      T07G12.1b
      T07G12.1c
    Corresponding_transcript (4)
    Other_sequence (28)
    Associated_feature: WBsf660585
      WBsf660586
      WBsf997639
      WBsf997640
      WBsf997641
      WBsf997642
      WBsf1018106
      WBsf1018107
      WBsf228999
  Experimental_info: RNAi_result: WBRNAi00052782 Inferred_automatically: RNAi_primary
      WBRNAi00035317 Inferred_automatically: RNAi_primary
      WBRNAi00076661 Inferred_automatically: RNAi_primary
      WBRNAi00018388 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr6632
      Expr1011751
      Expr1156389
      Expr2009704
      Expr2027943
    Drives_construct: WBCnstr00004019
      WBCnstr00037602
    Construct_product: WBCnstr00037602
    Microarray_results (22)
    Expression_cluster: WBPaper00024970:GABAergic_neuron_specific
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_larva_enriched
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044656:tatn-1(qd182)_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00048579:aging_upregulated
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050743:elli-1(sam-3)_downregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00051437:Cit-SPIONs_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055648:male-tail_expressed
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056284:ints-11(RNAi)_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058678:DAF-12_upregulated_PVD
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_enriched
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059471:EGL-43_interacting
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00059987:Wounding_upregulated
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061340:AFD
      WBPaper00061340:AIY
      WBPaper00061340:hmc
      WBPaper00061340:Rectal_cell
      WBPaper00061340:RIB
      WBPaper00061340:RIS
      WBPaper00061340:RIV
      WBPaper00061340:RME
      WBPaper00061340:SMD
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:xbx-3-DH11.5_20397
      WBPaper00061651:ADE_enriched
      WBPaper00061651:AWC_OFF_enriched
      WBPaper00061651:BDU_enriched
      WBPaper00061651:FLP_enriched
      WBPaper00061651:MC_enriched
      WBPaper00061651:PDA_enriched
      WBPaper00061651:PVD_enriched
      WBPaper00061651:PVW_enriched
      WBPaper00061651:RIB_enriched
      WBPaper00061651:RIG_enriched
      WBPaper00061651:RIH_enriched
      WBPaper00061651:RIS_enriched
      WBPaper00061651:SAB_enriched
      WBPaper00061651:SMD_enriched
      WBPaper00061651:URB_enriched
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062103:neuron_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064721:fasn-1(g14)_downregulated_starved
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065158:AFD_enriched
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065749:Heat-Shock_downregulated_N2
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065841:14_1
      WBPaper00065841:29_0
      WBPaper00065841:35_2
      WBPaper00065841:44_1
      WBPaper00065841:58_0
      WBPaper00065841:67_0
      WBPaper00065841:70_1
      WBPaper00065841:80_0
      WBPaper00065841:101_0
      WBPaper00065841:121_0
      WBPaper00065841:122_0
      WBPaper00065841:124_0
      WBPaper00065841:126_0
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      cgc4489_group_13
      WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00030839:Larval_A_Class
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00034739:N2moreDR1350
      WBPaper00035227:heat_shock_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00036286:Pattern_I
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040985:AIN-2_asynchronous_muscle
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00042548:miRISC_enriched
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:xpa-1_UV_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc6390]:male_sex-enriched
    Interaction (11)
  Map_info: Map: IV Position: 4.61636 Error: 0.000867
    Positive: Positive_clone: T07G12 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00019540
    WBPaper00023932
    WBPaper00030971
    WBPaper00050050
  Remark: Sequence connection from [Schulze E, Karabinos A, Weber K], 02/06/11 krb
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene