WormBase Tree Display for Gene: WBGene00000206
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| WBGene00000206 | SMap | S_parent | Sequence | F35G12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | asb-1 | Person_evidence | WBPerson284 | |||||
| Sequence_name | F35G12.10 | ||||||||
| Molecular_name | F35G12.10 | ||||||||
| F35G12.10.1 | |||||||||
| CE00968 | |||||||||
| Other_name | CELE_F35G12.10 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | asb-1 | ||||||||
| DB_info | Database | AceView | gene | 3F686 | |||||
| WormQTL | gene | WBGene00000206 | |||||||
| WormFlux | gene | WBGene00000206 | |||||||
| NDB | locus_tag | CELE_F35G12.10 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000206|UniProtKB=Q20053 | |||||||
| family | PTHR12733 | ||||||||
| NCBI | gene | 175605 | |||||||
| RefSeq | protein | NM_065537.7 | |||||||
| SwissProt | UniProtAcc | Q20053 | |||||||
| TREEFAM | TREEFAM_ID | TF313250 | |||||||
| UniProt_GCRP | UniProtAcc | Q20053 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | asb | ||||||||
| Allele (11) | |||||||||
| Strain | WBStrain00022689 | ||||||||
| WBStrain00022690 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Contained_in_operon | CEOP3204 | ||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00000207 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | asb-1 encodes the B subunit of the membrane-bound F0 proton channel portion of ATP synthase (mitochondrial respiratory chain [MRC] complex V) that is closely similar to its paralog ASB-2; asb-1 activity is required for embryonic viability and for normal proliferation of germline cells, specifically their progression to meiosis; in addition, asb-1 is required for response to hermaphrodite contact, the first step in a series of stereotypical male mating behaviors; expression of asb-1 mRNA is enriched in the germline and an ASB-1::GFP fusion localizes to mitochondria and to cilia of the male-specific CEM neurons. | Paper_evidence | WBPaper00005486 | |||||
| WBPaper00024944 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jan 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Located in mitochondrion and non-motile cilium. Expressed in germ line. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma and hepatocellular carcinoma. Is an ortholog of human ATP5PB (ATP synthase peripheral stalk-membrane subunit b). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:4467 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:840) | ||||
| DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:840) | ||||||
| Molecular_info | Corresponding_CDS | F35G12.10 | |||||||
| Corresponding_transcript | F35G12.10.1 | ||||||||
| Other_sequence (16) | |||||||||
| Associated_feature | WBsf666804 | ||||||||
| WBsf226553 | |||||||||
| WBsf226554 | |||||||||
| WBsf226555 | |||||||||
| Experimental_info | RNAi_result (24) | ||||||||
| Expr_pattern | Expr4494 | ||||||||
| Expr4496 | |||||||||
| Expr4498 | |||||||||
| Expr1018693 | |||||||||
| Expr1030125 | |||||||||
| Expr1150264 | |||||||||
| Expr2009443 | |||||||||
| Expr2027680 | |||||||||
| Drives_construct | WBCnstr00037665 | ||||||||
| Construct_product | WBCnstr00004944 | ||||||||
| WBCnstr00037665 | |||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (160) | |||||||||
| Interaction (213) | |||||||||
| WBProcess | WBbiopr:00000012 | ||||||||
| Map_info | Map | III | Position | -3.03261 | Error | 0.002151 | |||
| Positive | Positive_clone | F35G12 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Sequence connection from [Iino Y] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
