WormBase Tree Display for Gene: WBGene00000207
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| WBGene00000207 | SMap | S_parent | Sequence | F02E8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | asb-2 | Person_evidence | WBPerson284 | |||||
| Sequence_name | F02E8.1 | ||||||||
| Molecular_name | F02E8.1 | ||||||||
| F02E8.1.1 | |||||||||
| CE07016 | |||||||||
| F02E8.1.2 | |||||||||
| Other_name | CELE_F02E8.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | asb-2 | ||||||||
| DB_info | Database | AceView | gene | XF89 | |||||
| WormQTL | gene | WBGene00000207 | |||||||
| WormFlux | gene | WBGene00000207 | |||||||
| NDB | locus_tag | CELE_F02E8.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000207|UniProtKB=Q19126 | |||||||
| family | PTHR12733 | ||||||||
| NCBI | gene | 180718 | |||||||
| RefSeq | protein | NM_076369.6 | |||||||
| SwissProt | UniProtAcc | Q19126 | |||||||
| TREEFAM | TREEFAM_ID | TF313250 | |||||||
| UniProt_GCRP | UniProtAcc | Q19126 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | asb | ||||||||
| Allele (40) | |||||||||
| Strain | WBStrain00036803 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (38) | |||||||||
| Paralog | WBGene00000206 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | asb-2 encodes the B subunit of the membrane-bound F0 proton channel portion of ATP synthase (mitochondrial respiratory chain [MRC] complex V) that is closely similar to its paralog ASB-1; RNAi experiments indicate that asb-2 activity is required for larval development as well as for normal body morphology, lifespan, and growth rate. | Paper_evidence | WBPaper00006395 | |||||
| WBPaper00024497 | |||||||||
| WBPaper00024944 | |||||||||
| WBPaper00026715 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 17 Jan 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o). Expressed in several structures, including gonad. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma and hepatocellular carcinoma. Is an ortholog of human ATP5PB (ATP synthase peripheral stalk-membrane subunit b). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:4467 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:840) | ||||
| DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:840) | ||||||
| Molecular_info | Corresponding_CDS | F02E8.1 | |||||||
| Corresponding_transcript | F02E8.1.1 | ||||||||
| F02E8.1.2 | |||||||||
| Other_sequence (69) | |||||||||
| Associated_feature | WBsf648014 | ||||||||
| WBsf662689 | |||||||||
| WBsf1004953 | |||||||||
| WBsf1004954 | |||||||||
| WBsf1022789 | |||||||||
| WBsf1022790 | |||||||||
| WBsf235584 | |||||||||
| WBsf235585 | |||||||||
| WBsf235586 | |||||||||
| Experimental_info | RNAi_result (15) | ||||||||
| Expr_pattern | Expr4495 | ||||||||
| Expr4497 | |||||||||
| Expr13102 | |||||||||
| Expr1011605 | |||||||||
| Expr1030126 | |||||||||
| Expr1147794 | |||||||||
| Expr2009444 | |||||||||
| Expr2027681 | |||||||||
| Drives_construct | WBCnstr00037664 | ||||||||
| Construct_product | WBCnstr00037664 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (191) | |||||||||
| Interaction (154) | |||||||||
| Map_info | Map | X | Position | -7.53128 | Error | 0.017707 | |||
| Positive | Positive_clone | F02E8 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4268 | |||||||
| 4511 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Remark | Sequence connection from [Iino Y] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
