WormBase Tree Display for Gene: WBGene00000083
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| WBGene00000083 | Evidence | Person_evidence | WBPerson2345 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | CHROMOSOME_X | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | adt-2 | Person_evidence | WBPerson269 | |||||
| Sequence_name | F08C6.1 | ||||||||
| Molecular_name | F08C6.1a | ||||||||
| F08C6.1a.1 | |||||||||
| CE48012 | |||||||||
| F08C6.1b | |||||||||
| CE33991 | |||||||||
| F08C6.1c | |||||||||
| CE47865 | |||||||||
| F08C6.1b.1 | |||||||||
| F08C6.1c.1 | |||||||||
| Other_name | sma-21 | Paper_evidence | WBPaper00038069 | ||||||
| CELE_F08C6.1 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | adt-2 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 20 Oct 2011 16:17:23 | WBPerson2970 | Name_change | Other_name | sma-21 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | adt | ||||||||
| Allele (130) | |||||||||
| Strain | WBStrain00005159 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (32) | |||||||||
| Ortholog (45) | |||||||||
| Paralog | WBGene00000082 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00001650 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00086562 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00003242 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00009958 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00020567 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00021171 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003248 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | adt-2 encodes a member of the ADAMTS (a disintegrin and metalloprotease with thrombospodin motif) family of secreated metalloproteases; ADT-2 binds to extracellular matrix and is involved in remodeling of the extracellular matrix; homozygous adt-2 mutants die at the 3-fold stage of embryogenesis or during hatching; adult worms are about 20% reduced body length as compared to the wild type; adt-2 mutants have reduced lifespan with a median survival of 8 days from adulthood but have normal number of hypodermal nuclei; adt-2 is required for maintenance of body length as well as for increase in body length during growth stages; adt-2 regulate body size in part by modification of external cuticle; ADT-2 directly or indirectly regulates DBL-1 signaling activity; adt-2 expression is absent in embryos but is detected in glial cells associated with amphid, phasmid, labial and posterior deirids (PDE) sensory neurons during larval development and vulval tissue in L4 and adults. | Paper_evidence | WBPaper00038069 | |||||
| Curator_confirmed | WBPerson12884 | ||||||||
| Date_last_updated | 16 May 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable metalloendopeptidase activity. Involved in several processes, including collagen fibril organization; determination of adult lifespan; and regulation of cell size. Predicted to be located in extracellular matrix. Expressed in socket cell and vulva. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F08C6.1a | |||||||
| F08C6.1b | |||||||||
| F08C6.1c | |||||||||
| Corresponding_CDS_history | F08C6.1:wp98 | ||||||||
| Corresponding_transcript | F08C6.1a.1 | ||||||||
| F08C6.1b.1 | |||||||||
| F08C6.1c.1 | |||||||||
| Other_sequence (11) | |||||||||
| Associated_feature (18) | |||||||||
| Experimental_info | RNAi_result (21) | ||||||||
| Expr_pattern | Expr9197 | ||||||||
| Expr1012310 | |||||||||
| Expr1030039 | |||||||||
| Expr1147951 | |||||||||
| Expr2009245 | |||||||||
| Expr2027482 | |||||||||
| Drives_construct | WBCnstr00008188 | ||||||||
| WBCnstr00037745 | |||||||||
| Construct_product | WBCnstr00037745 | ||||||||
| Microarray_results | SMD_F08C6.1 | ||||||||
| 174723_at | |||||||||
| 189243_at | |||||||||
| A_12_P118174 | |||||||||
| A_12_P133405 | |||||||||
| A_12_P133406 | |||||||||
| A_12_P133407 | |||||||||
| A_12_P138050 | |||||||||
| A_12_P140291 | |||||||||
| A_12_P140292 | |||||||||
| Aff_F08C6.1 | |||||||||
| GPL13394_WBGene00000083 | |||||||||
| GPL13914_F08C6.1 | |||||||||
| GPL14144_F08C6.1a_2649-2708_0.936_6_C | |||||||||
| GPL14144_F08C6.1a_2983-3042_0.972_1_A | |||||||||
| GPL14144_F08C6.1a_2986-3045_0.969_2_B | |||||||||
| GPL19516_CGZ0014843 | |||||||||
| GPL19516_CGZ0014844 | |||||||||
| GPL19516_CGZ0014845 | |||||||||
| GPL19516_CGZ0014846 | |||||||||
| GPL19516_CGZ0014847 | |||||||||
| GPL21109_F08C6.1a.1 | |||||||||
| GPL21109_F08C6.1c.1 | |||||||||
| GPL3518_CE30936 | |||||||||
| GPL8304_CE_WBGene00000083_A | |||||||||
| GPL8304_CE_WBGene00000083_B | |||||||||
| GPL8673_F08C6_1aP01605 | |||||||||
| GPL8673_F08C6_1aP02294 | |||||||||
| GPL8673_F08C6_1aP02734 | |||||||||
| GPL8673_F08C6_1bP00049 | |||||||||
| GPL8673_F08C6_1bP00059 | |||||||||
| GPL8673_F08C6_1bP00241 | |||||||||
| GPL8673_F08C6_1cP01605 | |||||||||
| GPL8673_F08C6_1cP02295 | |||||||||
| GPL8673_F08C6_1cP02734 | |||||||||
| GPL9450_F08C6.1 | |||||||||
| cea2.p.139232 | |||||||||
| Expression_cluster (156) | |||||||||
| Interaction (28) | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| Map_info | Map | X | Position | -1.47889 | Error | 0.009854 | |||
| Positive | Positive_clone | F08C6 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5316 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038069 | ||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061662 | |||||||||
| WBPaper00063946 | |||||||||
| WBPaper00064099 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
