WormBase Tree Display for Gene: WBGene00000067
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| WBGene00000067 | SMap | S_parent | Sequence | T25C8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | act-5 | Person_evidence | WBPerson259 | |||||
| Sequence_name | T25C8.2 | ||||||||
| Molecular_name | T25C8.2 | ||||||||
| T25C8.2.1 | |||||||||
| CE16463 | |||||||||
| Other_name | CELE_T25C8.2 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | act-5 | ||||||||
| DB_info | Database | AceView | gene | 3O694 | |||||
| WormQTL | gene | WBGene00000067 | |||||||
| SignaLink | protein | WBGene00000067 | |||||||
| WormFlux | gene | WBGene00000067 | |||||||
| NDB | locus_tag | CELE_T25C8.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000067|UniProtKB=O45815 | |||||||
| family | PTHR11937 | ||||||||
| NCBI | gene | 176793 | |||||||
| RefSeq | protein | NM_067408.7 | |||||||
| TrEMBL | UniProtAcc | O45815 | |||||||
| UniProt_GCRP | UniProtAcc | O45815 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | act | ||||||||
| Allele (31) | |||||||||
| Legacy_information | [C.elegansII] NMK. Sequence predicts protein with closer similarity to vertebrate cytoplasmic actin than act-123, act-4. act-5:lacZ expressed only in microvillous intestinal cells and excretory cell. [RW] | ||||||||
| Strain | WBStrain00022158 | ||||||||
| WBStrain00022159 | |||||||||
| WBStrain00022160 | |||||||||
| WBStrain00036213 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00035313 | ||||||||
| 00035314 | |||||||||
| 00035315 | |||||||||
| 00035316 | |||||||||
| 00035317 | |||||||||
| 00035318 | |||||||||
| 00035319 | |||||||||
| Ortholog (36) | |||||||||
| Paralog (11) | |||||||||
| Structured_description | Concise_description | act-5 encodes an ortholog of human cytoplasmic actin; act-5 is required for formation of the terminal web and microvilli on the apical surface of intestinal cells; act-5 also plays a role in mediating non-lytic exit of intracellular parasites from the intestine; act-5 is expressed only in intestinal cells and in the excretory cell; in the intestine, ACT-5 localizes to microvilli and the terminal web. | Paper_evidence | WBPaper00025171 | |||||
| WBPaper00040246 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson480 | |||||||||
| Date_last_updated | 08 Apr 2014 00:00:00 | ||||||||
| Automated_description | Involved in several processes, including larval feeding behavior; microvillus assembly; and positive regulation of eating behavior. Located in microvillar actin bundle and terminal web. Expressed in excretory cell; gonad; intestine; pharyngeal-intestinal valve; and rectal gland cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T25C8.2 | |||||||
| Corresponding_transcript | T25C8.2.1 | ||||||||
| Other_sequence (149) | |||||||||
| Associated_feature (26) | |||||||||
| Experimental_info | RNAi_result (23) | ||||||||
| Expr_pattern | Expr3724 | ||||||||
| Expr4555 | |||||||||
| Expr4594 | |||||||||
| Expr14933 | |||||||||
| Expr1024157 | |||||||||
| Expr1030028 | |||||||||
| Expr1157664 | |||||||||
| Expr2009225 | |||||||||
| Expr2027462 | |||||||||
| Drives_construct (20) | |||||||||
| Construct_product (15) | |||||||||
| Antibody | WBAntibody00001016 | ||||||||
| WBAntibody00001783 | |||||||||
| WBAntibody00002552 | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (282) | |||||||||
| Interaction (460) | |||||||||
| Map_info | Map | III | Position | 21.292 | Error | 0.00233 | |||
| Positive | Positive_clone | T25C8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5609 | |||||||
| 5295 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (47) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
