WormBase Tree Display for Interaction: WBInteraction000549522
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| WBInteraction000549522 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00004055 | Interactor_type | Trans_regulator | |
| WBGene00001399 | Interactor_type | Trans_regulated | |||
| WBGene00000182 | Interactor_type | Trans_regulated | |||
| Interaction_summary | "Although not identified in our microarray study, irg-1 reproducibly increased after sams-1 RNAi in qRT-PCR experiments, requiring pmk-1 (Figure 2B). Thus, there may be some regulatory distinctions between low SAM and pathogen exposure. Loss of pmk-1 did not limit upregulation of lipogenic genes, or arf-1.1, the gene with the highest-fold increase in sams-1(RNAi) microarrays (Figure 2C), demonstrating that pmk-1 is not generally required for transcriptional changes in sams-1(RNAi) animals" | ||||
| Detection_method | RT_PCR | ||||
| Regulation_level | Transcriptional | ||||
| Paper | WBPaper00048490 | ||||
| Remark | Fig. 2c |
