WormBase Tree Display for Gene: WBGene00000182
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| WBGene00000182 | SMap | S_parent | Sequence | B0336 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | arf-1 | |||||||
| Sequence_name | B0336.2 | ||||||||
| Molecular_name | B0336.2 | ||||||||
| B0336.2.1 | |||||||||
| CE00696 | |||||||||
| B0336.2.2 | |||||||||
| Other_name | ARF/1 | ||||||||
| arf-1.2 | |||||||||
| CELE_B0336.2 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | arf-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 05 Nov 2004 15:32:14 | WBPerson2970 | Name_change | CGC_name | arf-1.2 | ||||
| 3 | 10 Sep 2020 13:24:17 | WBPerson1983 | Name_change | CGC_name | arf-1 | ||||
| Other_name | arf-1.2 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | arf | ||||||||
| Allele (33) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes 181 aa predicted class I ARF. [CGC, MQ] | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Contained_in_operon | CEOP3332 | ||||||||
| Ortholog (45) | |||||||||
| Paralog (14) | |||||||||
| Structured_description | Concise_description | arf-1.2 encodes an ADP-ribosylation factor homolog required in vivo for embryonic development, fertility, locomotion, vulval development, and cuticular synthesis; ARF proteins are N-myristoylated GTPases that regulate membrane traffic and the actin cytoskeleton, and that activate both phospholipase D1 (PLD1) and phosphatidylinositol 4-phosphate 5-kinase. | Paper_evidence | WBPaper00012958 | |||||
| WBPaper00013160 | |||||||||
| WBPaper00015195 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 16 Jul 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTP binding activity and GTPase activity. Involved in several processes, including oocyte development; regulation of apoptotic process involved in development; and regulation of receptor-mediated endocytosis. Located in endoplasmic reticulum. Expressed in pharyngeal muscle cell; uterus; ventral nerve cord; and vulval precursor cell. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Is an ortholog of human ARF1 (ADP ribosylation factor 1) and ARF3 (ADP ribosylation factor 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0050454 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:652) | ||||
| Molecular_info | Corresponding_CDS | B0336.2 | |||||||
| Corresponding_transcript | B0336.2.1 | ||||||||
| B0336.2.2 | |||||||||
| Other_sequence (178) | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result (38) | ||||||||
| Expr_pattern | Chronogram1686 | ||||||||
| Expr3149 | |||||||||
| Expr4834 | |||||||||
| Expr5055 | |||||||||
| Expr15679 | |||||||||
| Expr1028066 | |||||||||
| Expr1030106 | |||||||||
| Expr1143124 | |||||||||
| Expr2009391 | |||||||||
| Expr2027627 | |||||||||
| Drives_construct | WBCnstr00002999 | ||||||||
| WBCnstr00011177 | |||||||||
| WBCnstr00012265 | |||||||||
| WBCnstr00019869 | |||||||||
| WBCnstr00037680 | |||||||||
| WBCnstr00042476 | |||||||||
| Construct_product | WBCnstr00008785 | ||||||||
| WBCnstr00008786 | |||||||||
| WBCnstr00019869 | |||||||||
| WBCnstr00037680 | |||||||||
| WBCnstr00042476 | |||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (132) | |||||||||
| Interaction (182) | |||||||||
| Map_info | Map | III | Position | -1.44726 | Error | 0.000356 | |||
| Positive | Positive_clone | B0336 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| NM#G4 | |||||||||
| Mapping_data | Multi_point | 4788 | |||||||
| 5049 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (37) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| This gene was previously assigned the CGC name arf-1. It has been re-assigned to arf-1.2 | Curator_confirmed | WBPerson2970 | |||||||
| Method | Gene |
