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WormBase Tree Display for Interaction: WBInteraction000541603

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Name Class

WBInteraction000541603Interaction_typeRegulatoryChange_of_localization
InteractorInteractor_overlapping_geneWBGene00006943Interactor_typeTrans_regulated
Expr_patternExpr3683
TransgeneWBTransgene00001435
ConstructWBCnstr00001425
WBGene00000156Interactor_typeTrans_regulator
Interaction_summaryIn the wild-type T cell, WRM-1 always localized to the anterior cortex prior to cell division and to the posterior nucleus after the division. In apr-1(RNAi) animals, WRM-1 localization was always asymmetric to the anterior cortex. Therefore, apr-1 may not be required for cortical WRM-1 localization. In contrast to the normal cortical WRM-1 localization, in osIs5; apr-1(RNAi) animals, WRM-1 was distributed symmetrically in the nuclei of both T cell daughters.
Detection_methodConstruct
Reporter_gene[wrm-1::gfp], translational fusion under scm promoter.
Transgene
Regulation_levelPost_translational
Regulation_resultDoes_not_regulateSubcellular_localizationcortex
Interaction_RNAiWBRNAi00077089
PaperWBPaper00029082