WormBase Tree Display for Gene: WBGene00023451

WBGene00023451 SMap: S_parent: Sequence: K08E3
  Identity: Version: 2
    Name: CGC_name: mlc-7 Person_evidence: WBPerson260
      Sequence_name: K08E3.10
      Molecular_name: K08E3.10
        K08E3.10.1
        CE37122
      Other_name: CELE_K08E3.10 Accession_evidence: NDB BX284603
      Public_name: mlc-7
    DB_info: Database: AceView gene 3O843
        WormFlux gene WBGene00023451
        NDB locus_tag CELE_K08E3.10
        Panther gene CAEEL|WormBase=WBGene00023451|UniProtKB=Q69Z12
          family PTHR23048
        NCBI gene 176811
        RefSeq protein NM_001027498.6
        TrEMBL UniProtAcc Q69Z12
        UniProt_GCRP UniProtAcc Q69Z12
        OMIM gene 160770
            160780
            160790
    Species: Caenorhabditis elegans
    History: Version_change: 1 22 Jul 2004 11:38:37 WBPerson1983 Event: Split_from: WBGene00010663
        2 03 May 2013 15:28:52 WBPerson2970 Name_change: CGC_name: mlc-7
      Split_from: WBGene00010663
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mlc
    Allele (47)
    RNASeq_FPKM (74)
    GO_annotation: 00081774
      00126867
    Ortholog (56)
    Paralog: WBGene00003371 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009585 Caenorhabditis elegans From_analysis: Panther
      WBGene00010554 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00011734 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable calcium ion binding activity. Predicted to be part of myosin II complex. Human ortholog(s) of this gene implicated in congenital myopathy 14; familial atrial fibrillation; and hypertrophic cardiomyopathy 8. Is an ortholog of several human genes including MYL1 (myosin light chain 1); MYL3 (myosin light chain 3); and MYL4 (myosin light chain 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0081346 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7582)
      DOID:0050650 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7585)
      DOID:0050700 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7585)
      DOID:0110314 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7584)
  Molecular_info: Corresponding_CDS: K08E3.10
    Corresponding_transcript: K08E3.10.1
    Other_sequence: CB037810.1
      CB037959.1
      CB038290.1
      MH05891
      Tcir_isotig05272
      Tcir_isotig05273
      TDC00984_1
      Dviv_isotig22409
      Dviv_isotig22408
    Associated_feature: WBsf226062
  Experimental_info: RNAi_result: WBRNAi00050283 Inferred_automatically: RNAi_primary
      WBRNAi00006275 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1018557
      Expr1153983
      Expr2013595
      Expr2031828
    Drives_construct: WBCnstr00023871
    Construct_product: WBCnstr00023871
    Microarray_results (16)
    Expression_cluster (151)
    Interaction: WBInteraction000552512
      WBInteraction000554971
      WBInteraction000561156
      WBInteraction000564059
  Map_info: Map: III Position: 21.4657
    Positive: Positive_clone: K08E3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene