WormBase Tree Display for Gene: WBGene00003371
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| WBGene00003371 | SMap | S_parent | Sequence | F09F7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | mlc-3 | Person_evidence | WBPerson21 | |||||
| Sequence_name | F09F7.2 | ||||||||
| Molecular_name | F09F7.2a | ||||||||
| F09F7.2a.1 | |||||||||
| CE01236 | |||||||||
| F09F7.2b | |||||||||
| CE30652 | |||||||||
| F09F7.2a.2 | |||||||||
| F09F7.2b.1 | |||||||||
| Other_name | CELE_F09F7.2 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | mlc-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mlc | ||||||||
| Allele (34) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes alkali (essential) MLC; >40% identity to vertebrate and invertebrate MLC.Transcripts 1.05 kb, 0.75 kb. [TR] | ||||||||
| Strain | WBStrain00002370 | ||||||||
| WBStrain00002883 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00021121 | ||||||||
| 00021122 | |||||||||
| 00047966 | |||||||||
| 00110796 | |||||||||
| Ortholog (51) | |||||||||
| Paralog | WBGene00011734 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00010554 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00009585 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00023451 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | mlc-3 encodes an essential myosin light chain; large-scale RNAi screens indicate that mlc-3 activity is required for both embryonic and postembryonic development, as well as for normal locomotion and egg laying. | Paper_evidence | WBPaper00001230 | |||||
| WBPaper00003624 | |||||||||
| WBPaper00004403 | |||||||||
| WBPaper00005654 | |||||||||
| WBPaper00006395 | |||||||||
| WBPaper00024497 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 13 Oct 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable calcium ion binding activity. Located in striated muscle myosin thick filament. Expressed in head neurons; nervous system; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy 8. Is an ortholog of human MYL3 (myosin light chain 3) and MYL6B (myosin light chain 6B). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110314 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7584) | ||||
| Molecular_info | Corresponding_CDS | F09F7.2a | |||||||
| F09F7.2b | |||||||||
| Corresponding_transcript | F09F7.2a.1 | ||||||||
| F09F7.2a.2 | |||||||||
| F09F7.2b.1 | |||||||||
| Other_sequence (250) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern | Chronogram945 | ||||||||
| Expr5703 | |||||||||
| Expr9360 | |||||||||
| Expr1018734 | |||||||||
| Expr1031550 | |||||||||
| Expr1148121 | |||||||||
| Expr2013591 | |||||||||
| Expr2031824 | |||||||||
| Drives_construct | WBCnstr00003020 | ||||||||
| WBCnstr00004502 | |||||||||
| WBCnstr00036154 | |||||||||
| Construct_product | WBCnstr00013925 | ||||||||
| WBCnstr00036154 | |||||||||
| Microarray_results (32) | |||||||||
| Expression_cluster (258) | |||||||||
| Interaction (48) | |||||||||
| Map_info | Map | III | Position | -1.54187 | Error | 0.002181 | |||
| Positive | Positive_clone | F09F7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| MLC4C | |||||||||
| Pseudo_map_position | |||||||||
| Reference (12) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
