WormBase Tree Display for Gene: WBGene00018474
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| WBGene00018474 | SMap | S_parent | Sequence | F45E12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | cnep-1 | Person_evidence | WBPerson1816 | |||||
| WBPerson56 | |||||||||
| Sequence_name | F45E12.1 | ||||||||
| Molecular_name | F45E12.1a | ||||||||
| F45E12.1a.1 | |||||||||
| CE02737 | |||||||||
| F45E12.1b | |||||||||
| CE46930 | |||||||||
| F45E12.1a.2 | |||||||||
| F45E12.1b.1 | |||||||||
| Other_name | scpl-2 | Person_evidence | WBPerson56 | ||||||
| CELE_F45E12.1 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | cnep-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 02 Feb 2007 10:20:45 | WBPerson2970 | Name_change | CGC_name | scpl-2 | ||||
| 3 | 22 Jan 2013 16:23:13 | WBPerson2970 | Name_change | CGC_name | cnep-1 | ||||
| Other_name | scpl-2 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cnep | ||||||||
| Allele (43) | |||||||||
| Strain | WBStrain00001252 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (24) | |||||||||
| Ortholog (35) | |||||||||
| Paralog | WBGene00007054 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00011897 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00021629 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | cnep-1 encodes a putative serine/threonine phosphatase, orthologous to budding yeast Nem1p and human DULLARD; CNEP-1 is expressed in pharynx and intestine; CNEP-1 is distantly similar to FCP-1 and SCPL-1, -3, and -4; by homology, CNEP-1 is predicted to reside in the endoplasmic reticulum membrane in a complex with SPO-7 that functions to dephosphorylate the phosphatidic acid phosphatase LPIN-1 and thus regulate phospholipid metabolism; loss of cnep-1 activity via RNAi results in a twinned nuclei phenotype in which the embryonic blastomeres AB and P1 contain two nuclei; the twinned nuclei phenotype is also seen in embryos lacking spo-7 and lpin-1 activity. | Paper_evidence (5) | ||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 23 Mar 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable protein serine/threonine phosphatase activity. Involved in nuclear membrane reassembly and regulation of nuclear division. Located in nuclear envelope. Is an ortholog of human CTDNEP1 (CTD nuclear envelope phosphatase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F45E12.1a | |||||||
| F45E12.1b | |||||||||
| Corresponding_transcript | F45E12.1a.1 | ||||||||
| F45E12.1a.2 | |||||||||
| F45E12.1b.1 | |||||||||
| Other_sequence (26) | |||||||||
| Associated_feature | WBsf644372 | ||||||||
| WBsf657815 | |||||||||
| WBsf657816 | |||||||||
| WBsf988397 | |||||||||
| WBsf221586 | |||||||||
| WBsf221587 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00047393 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00111105 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061811 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047396 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047398 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015019 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00022362 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032298 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr6077 | ||||||||
| Expr11677 | |||||||||
| Expr1027913 | |||||||||
| Expr1037962 | |||||||||
| Expr1151241 | |||||||||
| Expr2010271 | |||||||||
| Expr2028513 | |||||||||
| Drives_construct | WBCnstr00002146 | ||||||||
| WBCnstr00019173 | |||||||||
| WBCnstr00019174 | |||||||||
| WBCnstr00037831 | |||||||||
| Construct_product | WBCnstr00019173 | ||||||||
| WBCnstr00019174 | |||||||||
| WBCnstr00037831 | |||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (72) | |||||||||
| Interaction (22) | |||||||||
| Map_info | Map | II | Position | 0.501491 | Error | 6.6e-05 | |||
| Positive | Positive_clone | F45E12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (9) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
