Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00017981

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00017981SMapS_parentSequenceCHROMOSOME_V
IdentityVersion3
NameCGC_namefigl-1Paper_evidenceWBPaper00024642
Person_evidenceWBPerson4034
WBPerson4369
WBPerson4370
Sequence_nameF32D1.1
Molecular_nameF32D1.1a
F32D1.1a.1
CE09865
F32D1.1b
CE51584
F32D1.1c
CE51574
F32D1.1b.1
F32D1.1c.1
Other_nameCELE_F32D1.1Accession_evidenceNDBBX284605
Public_namefigl-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:59WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
219 Dec 2005 11:47:52WBPerson2970Name_changeCGC_namefign-1
306 Jan 2006 11:32:15WBPerson2970Name_changeCGC_namefigl-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfigl
Allele (136)
RNASeq_FPKM (74)
GO_annotation (29)
Contained_in_operonCEOP5052
Ortholog (45)
ParalogWBGene00003183Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00010047Caenorhabditis elegansFrom_analysisPanther
WBGene00011175Caenorhabditis elegansFrom_analysisPanther
WBGene00016045Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00021334Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00010557Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionfigl-1 encodes an homolog of human SPASTIN (OMIM:604277, mutated in spastic paraplegia), FIDGETIN (OMIM:605295, mutated in fidget mice), and FIDGETIN-LIKE-1, and of Drosophila SPASTIN; recombinant FIGL-1 protein has N-ethylmaleimide-sensitive ATPase activity in vitro, which is strongly dependent on the C368 residue immediately C-terminal to its Walker A motif; figl-1 is required for persistence of the germline in RNAi assays.Paper_evidenceWBPaper00024642
WBPaper00025054
WBPaper00027331
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated21 Dec 2010 00:00:00
Automated_descriptionEnables ATP hydrolysis activity; magnesium ion binding activity; and microtubule binding activity. Involved in ATP metabolic process and positive regulation of mitotic cell cycle. Located in nucleus. Expressed in germ line. Is an ortholog of human FIGNL1 (fidgetin like 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF32D1.1a
F32D1.1b
F32D1.1c
Corresponding_transcriptF32D1.1a.1
F32D1.1b.1
F32D1.1c.1
Other_sequence (39)
Associated_featureWBsf652565
WBsf233567
WBsf233568
Experimental_infoRNAi_resultWBRNAi00111579Inferred_automaticallyRNAi_primary
WBRNAi00031671Inferred_automaticallyRNAi_primary
WBRNAi00046121Inferred_automaticallyRNAi_primary
WBRNAi00106244Inferred_automaticallyRNAi_primary
Expr_patternExpr7811
Expr10050
Expr1022570
Expr1037737
Expr1150004
Expr2011760
Expr2029998
Drives_constructWBCnstr00026868
Construct_productWBCnstr00026868
AntibodyWBAntibody00001081
WBAntibody00001296
WBAntibody00002340
Microarray_results (21)
Expression_cluster (80)
Interaction (69)
Map_infoMapVPosition-5.91118Error0.006405
PositivePositive_cloneF32D1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5652
5427
Pseudo_map_position
Reference (11)
RemarkWBGene00017981 has been renamed from fign-1 to figl-1 on the advice of the CGCCGC_data_submission
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene