WormBase Tree Display for Gene: WBGene00016655
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| WBGene00016655 | SMap | S_parent | Sequence | C44E4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | acbp-1 | Person_evidence | WBPerson344 | |||||
| Sequence_name | C44E4.6 | ||||||||
| Molecular_name | C44E4.6 | ||||||||
| C44E4.6.1 | |||||||||
| CE08720 | |||||||||
| C44E4.6.2 | |||||||||
| Other_name | CELE_C44E4.6 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | acbp-1 | ||||||||
| DB_info | Database | AceView | gene | 1F204 | |||||
| WormQTL | gene | WBGene00016655 | |||||||
| WormFlux | gene | WBGene00016655 | |||||||
| NDB | locus_tag | CELE_C44E4.6 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00016655|UniProtKB=O01805 | |||||||
| family | PTHR23310 | ||||||||
| NCBI | gene | 172071 | |||||||
| RefSeq | protein | NM_059011.8 | |||||||
| SwissProt | UniProtAcc | O01805 | |||||||
| TREEFAM | TREEFAM_ID | TF315078 | |||||||
| UniProt_GCRP | UniProtAcc | O01805 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:57 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 01 Apr 2005 11:05:24 | WBPerson2970 | Name_change | CGC_name | acbp-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | acbp | ||||||||
| Allele (28) | |||||||||
| Strain | WBStrain00033090 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00025731 | ||||||||
| 00025732 | |||||||||
| 00025733 | |||||||||
| 00025734 | |||||||||
| 00025735 | |||||||||
| 00122228 | |||||||||
| Contained_in_operon | CEOP1196 | ||||||||
| Ortholog (36) | |||||||||
| Paralog | WBGene00001153 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00007680 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00009818 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00012457 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00044603 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00018949 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | acbp-1 encodes a highly conserved protein containing a functional acyl-CoA-binding binding domain orthologous to human DBI (Diazepam Binding inhibitor) (OMIM: 125950) required for protein stability and ligand binding; acyl-CoA proteins are required for lipid droplet morphology and lipid storage function; acbp-1 mutants have reduced triglycerides, aberrant lipid droplet morphology and number in the intestine; mutants contain approximately 70% fewer but 3.8 times enlarged than that of the average lipid droplet; loss of ACBP-1 results in increased lipid chain unsaturation by 1.25 times; disruption of ACBP-1 function significantly reduces worm life span from 14 to 9 days; ACBP-1::GFP is predominantly expressed in intestine of L4 larvae. | Paper_evidence | WBPaper00038378 | |||||
| Curator_confirmed | WBPerson12884 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 16 May 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable long-chain fatty acyl-CoA binding activity. Involved in determination of adult lifespan and lipid storage. Is an ortholog of human DBI (diazepam binding inhibitor, acyl-CoA binding protein). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C44E4.6 | |||||||
| Corresponding_transcript | C44E4.6.1 | ||||||||
| C44E4.6.2 | |||||||||
| Other_sequence | GR14873 | ||||||||
| Tcir_isotig20858 | |||||||||
| Tcol_isotig21312 | |||||||||
| MH10887 | |||||||||
| JI472356.1 | |||||||||
| ASC17443_1 | |||||||||
| Dviv_isotig15304 | |||||||||
| Tcir_isotig10732 | |||||||||
| ES408833.1 | |||||||||
| Acan_isotig12435 | |||||||||
| Associated_feature | WBsf649109 | ||||||||
| WBsf649110 | |||||||||
| WBsf664159 | |||||||||
| WBsf219293 | |||||||||
| WBsf219294 | |||||||||
| Experimental_info (7) | |||||||||
| Map_info | Map | I | Position | -1.03673 | Error | 0.000586 | |||
| Positive | Positive_clone | C44E4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (8) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
