WormBase Tree Display for Gene: WBGene00010403
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WBGene00010403 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | otpl-8 | |||||||
Sequence_name | H19J13.1 | ||||||||
Molecular_name | H19J13.1 | ||||||||
H19J13.1.1 | |||||||||
CE51331 | |||||||||
Other_name | CELE_H19J13.1 | Accession_evidence | NDB | BX284606 | |||||
Public_name | otpl-8 | ||||||||
DB_info | Database | AceView | gene | XM884 | |||||
WormQTL | gene | WBGene00010403 | |||||||
WormFlux | gene | WBGene00010403 | |||||||
NDB | locus_tag | CELE_H19J13.1 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00010403|UniProtKB=G5EDX5 | |||||||
family | PTHR21522 | ||||||||
NCBI | gene | 186752 | |||||||
RefSeq | protein | NM_077644.6 | |||||||
TREEFAM | TREEFAM_ID | TF313428 | |||||||
TrEMBL | UniProtAcc | G5EDX5 | |||||||
UniProt_GCRP | UniProtAcc | G5EDX5 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:51 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 07 Apr 2008 11:28:34 | WBPerson2970 | Name_change | CGC_name | otpl-8 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | otpl | ||||||||
Allele (65) | |||||||||
Strain | WBStrain00050999 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (13) | |||||||||
Ortholog (45) | |||||||||
Paralog | WBGene00017034 | Caenorhabditis elegans | From_analysis (2) | ||||||
WBGene00018478 | Caenorhabditis elegans | From_analysis (3) | |||||||
WBGene00018479 | Caenorhabditis elegans | From_analysis (3) | |||||||
WBGene00018480 | Caenorhabditis elegans | From_analysis (4) | |||||||
WBGene00015035 | Caenorhabditis elegans | From_analysis (3) | |||||||
WBGene00017449 | Caenorhabditis elegans | From_analysis (3) | |||||||
WBGene00018477 | Caenorhabditis elegans | From_analysis (3) | |||||||
Structured_description | Concise_description | otpl-8 encodes an ortholog of otopetrins such as human OTOP1 (OMIM:607806), OTOP2 (OMIM:607827), and OTOP3 (OMIM:607828), along with other homologs in fish and insects (such as crustacean OTOPLb); otopetrins are predicted to have 12 transmembrane helices; by homology with OTOP1 and OTOPLb, OTPL-8 might regulate intracellular calcium fluxes during extracellular stimuli, promote extracellular calcium carbonate biomineralization, or both; OTPL-8's paralogs include OTPL-1 through OTPL-7; OTPL-8 has no function in mass RNAi assays. | Paper_evidence | WBPaper00031620 | |||||
WBPaper00031621 | |||||||||
WBPaper00031622 | |||||||||
WBPaper00031623 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 04 Apr 2008 00:00:00 | ||||||||
Automated_description | Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP1 (otopetrin 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | H19J13.1 | |||||||
Corresponding_CDS_history | H19J13.1:wp252 | ||||||||
Corresponding_transcript | H19J13.1.1 | ||||||||
Other_sequence | BM01130 | ||||||||
Associated_feature | WBsf1007263 | ||||||||
WBsf1007264 | |||||||||
WBsf238053 | |||||||||
Experimental_info | RNAi_result | WBRNAi00033722 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00016278 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00049429 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1025873 | ||||||||
Expr1153157 | |||||||||
Expr2014664 | |||||||||
Expr2032897 | |||||||||
Drives_construct | WBCnstr00031440 | ||||||||
Construct_product | WBCnstr00031440 | ||||||||
Microarray_results (16) | |||||||||
Expression_cluster (90) | |||||||||
Interaction | WBInteraction000153287 | ||||||||
WBInteraction000413423 | |||||||||
Map_info | Map | X | Position | 7.0159 | |||||
Positive | Positive_clone | H19J13 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (4) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |