WormBase Tree Display for Gene: WBGene00006524
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| WBGene00006524 | SMap | S_parent | Sequence | C44H4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | tap-1 | Person_evidence | WBPerson1315 | |||||
| Sequence_name | C44H4.5 | ||||||||
| Molecular_name | C44H4.5 | ||||||||
| C44H4.5.1 | |||||||||
| CE08726 | |||||||||
| Other_name | CELE_C44H4.5 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | tap-1 | ||||||||
| DB_info | Database | AceView | gene | XP209 | |||||
| WormQTL | gene | WBGene00006524 | |||||||
| WormFlux | gene | WBGene00006524 | |||||||
| NDB | locus_tag | CELE_C44H4.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006524|UniProtKB=G5EEM6 | |||||||
| family | PTHR47992 | ||||||||
| NCBI | gene | 181556 | |||||||
| RefSeq | protein | NM_078027.7 | |||||||
| SwissProt | UniProtAcc | G5EEM6 | |||||||
| TREEFAM | TREEFAM_ID | TF317785 | |||||||
| UniProt_GCRP | UniProtAcc | G5EEM6 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tap | ||||||||
| Allele (49) | |||||||||
| Strain | WBStrain00002712 | ||||||||
| WBStrain00035686 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (28) | |||||||||
| Paralog | WBGene00001412 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00006460 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00009354 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00011953 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00016580 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00018362 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00021856 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00022832 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | tap-1 encodes the C. elegans ortholog of the vertebrate TAB1 (TGF-beta activated kinase 1/MAP3K7 binding protein 1) protein; tap-1 is required, together with mom-4, for endodermal cell fate specification in the developing embryo; when co-expressed in vitro, TAP-1 binds MOM-4, the C. elegans TAK1 ortholog, and positively regulates MOM-4 MAPKKK activity. | Paper_evidence | WBPaper00003574 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Mar 2010 00:00:00 | ||||||||
| Automated_description | Enables mitogen-activated protein kinase kinase kinase binding activity and protein kinase activator activity. Involved in endodermal cell fate specification and negative regulation of Ras protein signal transduction. Predicted to be located in cytosol and nucleus. Expressed in cholinergic neurons; coelomocyte; and somatic neurons. Is an ortholog of human TAB1 (TGF-beta activated kinase 1 (MAP3K7) binding protein 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C44H4.5 | |||||||
| Corresponding_transcript | C44H4.5.1 | ||||||||
| Other_sequence | CBC06475_1 | ||||||||
| Associated_feature | WBsf648739 | ||||||||
| WBsf648740 | |||||||||
| WBsf655232 | |||||||||
| WBsf236693 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Chronogram1584 | ||||||||
| Expr3540 | |||||||||
| Expr3631 | |||||||||
| Expr5504 | |||||||||
| Expr1018368 | |||||||||
| Expr1032677 | |||||||||
| Expr1146485 | |||||||||
| Expr2017297 | |||||||||
| Expr2035432 | |||||||||
| Drives_construct | WBCnstr00003251 | ||||||||
| WBCnstr00011464 | |||||||||
| WBCnstr00034325 | |||||||||
| Construct_product | WBCnstr00011556 | ||||||||
| WBCnstr00034325 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (85) | |||||||||
| Interaction (67) | |||||||||
| Map_info | Map | X | Position | 17.6339 | Error | 0.418804 | |||
| Positive | Positive_clone | C44H4 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4719 | |||||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Picture | WBPicture0000013084 | ||||||||
| Remark | Sequence connection from [Ono K, Matsumoto K]. krb 13/11/01 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
