WormBase Tree Display for Gene: WBGene00004303
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WBGene00004303 | SMap | S_parent | Sequence | C29E4 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | ran-2 | |||||||
Sequence_name | C29E4.3 | ||||||||
Molecular_name (7) | |||||||||
Other_name | pna-3 | Person_evidence | WBPerson561 | ||||||
CELE_C29E4.3 | Accession_evidence | NDB | BX284603 | ||||||
Public_name | ran-2 | ||||||||
DB_info | Database | AceView | gene | 3J25 | |||||
WormQTL | gene | WBGene00004303 | |||||||
WormFlux | gene | WBGene00004303 | |||||||
NDB | locus_tag | CELE_C29E4.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00004303|UniProtKB=P34342 | |||||||
family | PTHR24113 | ||||||||
NCBI | gene | 176115 | |||||||
RefSeq | protein | NM_171884.5 | |||||||
NM_171198.8 | |||||||||
SwissProt | UniProtAcc | P34342 | |||||||
TREEFAM | TREEFAM_ID | TF318283 | |||||||
UniProt_GCRP | UniProtAcc | P34342 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 06 Jul 2015 11:34:19 | WBPerson2970 | Event | Acquires_merge | WBGene00004067 | ||||
Name_change | Other_name | pna-3 | |||||||
Acquires_merge | WBGene00004067 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | ran | ||||||||
Allele (51) | |||||||||
Legacy_information | [Schnabel H] maternal effect embryonic lethal with abnormal pronuclear apppearance | ||||||||
Strain | WBStrain00036599 | ||||||||
WBStrain00007779 | |||||||||
WBStrain00054780 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (13) | |||||||||
Contained_in_operon | CEOP3465 | ||||||||
Ortholog (47) | |||||||||
Structured_description | Concise_description | ran-2 encodes the C. elegans RanGAP (GTPase activating protein) homolog, conserved amongst yeast, Drosophila (segregation distorter), Xenopus, and humans; by homology, RAN-2 is predicted to function as a key regulator of the Ran GTP/GDP cycle by stimulating the otherwise weak Ran GTPase activity; in C. elegans, RAN-2 activity is essential during early embryogenesis for comigration of centrosomes with the male pronucleus, mitotic spindle formation, chromosome segregation, and nuclear envelope assembly; in addition, RAN-2 is also required for nucleocytoplasmic transport; ran-2 reporter gene expression is detected in embryos and larvae. | Paper_evidence (5) | ||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable GTPase activator activity and small GTPase binding activity. Involved in embryo development. Predicted to be located in cytosol; nucleus; and perinuclear region of cytoplasm. Expressed in intestinal cell. Is an ortholog of human RANGAP1 (Ran GTPase activating protein 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | C29E4.3a | |||||||
C29E4.3b | |||||||||
Corresponding_CDS_history | C29E4.3a:wp130 | ||||||||
Corresponding_transcript | C29E4.3a.1 | ||||||||
C29E4.3b.1 | |||||||||
C29E4.3b.2 | |||||||||
Other_sequence (24) | |||||||||
Associated_feature | WBsf645370 | ||||||||
WBsf645371 | |||||||||
WBsf976236 | |||||||||
WBsf976237 | |||||||||
WBsf225302 | |||||||||
WBsf225303 | |||||||||
WBsf225304 | |||||||||
WBsf225305 | |||||||||
Experimental_info | RNAi_result | WBRNAi00085739 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00062934 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00062949 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00001007 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00041448 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00086891 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00062955 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00002456 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00062942 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00065354 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr2038 | ||||||||
Expr1026981 | |||||||||
Expr1032128 | |||||||||
Expr1145479 | |||||||||
Expr2015251 | |||||||||
Expr2033485 | |||||||||
Microarray_results (20) | |||||||||
Expression_cluster (122) | |||||||||
Interaction (111) | |||||||||
Map_info | Map | III | Position | -0.48356 | Error | 0.002198 | |||
Positive | Positive_clone | C29E4 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference (11) | |||||||||
Remark (2) | |||||||||
Method | Gene |