WormBase Tree Display for Gene: WBGene00003864
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WBGene00003864 | SMap | S_parent | Sequence | CHROMOSOME_IV | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | oma | ||||||
Allele (56) | |||||||
Strain | WBStrain00035069 | ||||||
WBStrain00035066 | |||||||
WBStrain00035067 | |||||||
WBStrain00035068 | |||||||
WBStrain00040433 | |||||||
WBStrain00040434 | |||||||
WBStrain00048324 | |||||||
WBStrain00052677 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (55) | |||||||
Contained_in_operon | CEOP4312 | ||||||
Ortholog (51) | |||||||
Paralog (20) | |||||||
Structured_description | Concise_description | oma-1 encodes a zinc finger protein of the TIS11 finger type that is paralogous to OMA-2; while either oma-1 or oma-2 individually have no obvious mutant phenotype, oma-1 and oma-2 doubly mutant animals show defects in oocyte maturation, indicating that the two genes function redundantly in this process; whereas normal oocytes are released from meiotic prophase I arrest during oocyte maturation, oma-1;oma-2 mutant oocytes initiate, but fail to complete, maturation, arresting at a defined point in meiotic prophase I; the meiotic arrest of oma-1;oma-2 mutant oocytes is suppressed by wee-1.3(RNAi), implying that progression through meiotic prophase I is critically dependent on inhibition of WEE-1.3 by either OMA-1 or OMA-2; OMA-1 is expressed primarily in maturing oocytes, is cytoplasmic and visible prior to cellularization. | Paper_evidence | WBPaper00005198 | |||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 19 Mar 2012 00:00:00 | ||||||
Automated_description | Enables mRNA 3'-UTR AU-rich region binding activity and mRNA regulatory element binding translation repressor activity. Involved in several processes, including negative regulation of cell differentiation; oocyte development; and regulation of reproductive process. Located in P granule and centrosome. Part of messenger ribonucleoprotein complex. Expressed in several structures, including head muscle; neurons; oocyte; somatic nervous system; and vulva. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | EFO:MONDO:0014769 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1108) | ||
Molecular_info | Corresponding_CDS | C09G9.6 | |||||
Corresponding_transcript | C09G9.6.1 | ||||||
Other_sequence | XIC01512_1 | ||||||
HG11531 | |||||||
XI03775 | |||||||
SRC08713_1 | |||||||
FC813056.1 | |||||||
Associated_feature (15) | |||||||
Gene_product_binds | WBsf034245 | ||||||
Transcription_factor | WBTranscriptionFactor000116 | ||||||
Experimental_info | RNAi_result (29) | ||||||
Expr_pattern (16) | |||||||
Drives_construct (13) | |||||||
Construct_product (14) | |||||||
Antibody | WBAntibody00000486 | ||||||
WBAntibody00000547 | |||||||
WBAntibody00001073 | |||||||
WBAntibody00001074 | |||||||
WBAntibody00001087 | |||||||
WBAntibody00001664 | |||||||
WBAntibody00002447 | |||||||
Microarray_results (20) | |||||||
Expression_cluster (207) | |||||||
Interaction (354) | |||||||
WBProcess | WBbiopr:00000068 | ||||||
WBbiopr:00000073 | |||||||
Map_info | Map | IV | Position | 3.99916 | Error | 0.001096 | |
Positive | Positive_clone | C09G9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data (2) | |||||||
Reference (94) | |||||||
Picture | WBPicture0000013094 | ||||||
Remark | Weak rescue of the zu405 embryonic lethality [Lin, R][021017 ck1] | ||||||
Sequence connection based on Lin, R [021017 ck1] | |||||||
Sequence connection from [Shimada M], [krb 020711] | |||||||
Postitive method is weak rescue of the zu405 embryonic lethality | |||||||
Method | Gene |