WormBase Tree Display for Gene: WBGene00002259
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WBGene00002259 | SMap | S_parent | Sequence | T22G5 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | lbp-7 | Person_evidence | WBPerson492 | |||||
Sequence_name | T22G5.2 | ||||||||
Molecular_name | T22G5.2 | ||||||||
T22G5.2.1 | |||||||||
CE13984 | |||||||||
Other_name | CELE_T22G5.2 | Accession_evidence | NDB | BX284605 | |||||
Public_name | lbp-7 | ||||||||
DB_info | Database | AceView | gene | 5O359 | |||||
WormQTL | gene | WBGene00002259 | |||||||
WormFlux | gene | WBGene00002259 | |||||||
NDB | locus_tag | CELE_T22G5.2 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00002259|UniProtKB=O02323 | |||||||
family | PTHR11955 | ||||||||
NCBI | gene | 191701 | |||||||
RefSeq | protein | NM_074039.2 | |||||||
SwissProt | UniProtAcc | O02323 | |||||||
UniProt_GCRP | UniProtAcc | O02323 | |||||||
OMIM | gene | 170715 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:27 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | lbp | ||||||||
Allele (21) | |||||||||
Strain | WBStrain00037908 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00027057 | ||||||||
00027058 | |||||||||
00027059 | |||||||||
00027060 | |||||||||
00027061 | |||||||||
00110324 | |||||||||
Ortholog (52) | |||||||||
Paralog | WBGene00002253 | ||||||||
WBGene00002254 | |||||||||
WBGene00002255 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
WBGene00002256 | |||||||||
WBGene00002257 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00002258 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00002260 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00021486 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | lbp-7 encodes a predicted intracellular fatty acid binding protein (iFABP) that is most similar to the vertebrate muscle and heart FABPs; by homology, LBP-7 is predicted to function as an intracellular transporter for small hydrophobic molecules such as lipids and steroid hormones; as loss of lbp-7 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of LBP-7 in C. elegans development and/or behavior is not yet known. | Paper_evidence | WBPaper00003911 | |||||
WBPaper00005654 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable fatty acid binding activity. Predicted to be involved in fatty acid transport. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Charcot-Marie-Tooth disease type 1G; Down syndrome; and artery disease (multiple). Is an ortholog of several human genes including FABP3 (fatty acid binding protein 3); FABP7 (fatty acid binding protein 7); and PMP2 (peripheral myelin protein 2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model (11) | ||||||||
Molecular_info | Corresponding_CDS | T22G5.2 | |||||||
Corresponding_transcript | T22G5.2.1 | ||||||||
Other_sequence (6) | |||||||||
Associated_feature | WBsf716840 | ||||||||
WBsf1001903 | |||||||||
WBsf232840 | |||||||||
Experimental_info | RNAi_result | WBRNAi00095433 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00035824 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00102648 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00053855 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00019041 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00088960 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00063219 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (4) | |||||||||
Drives_construct | WBCnstr00036352 | ||||||||
Construct_product | WBCnstr00036352 | ||||||||
Microarray_results (19) | |||||||||
Expression_cluster (227) | |||||||||
Interaction (12) | |||||||||
WBProcess | WBbiopr:00000039 | ||||||||
Map_info | Map | V | Position | 5.70567 | Error | 0.00122 | |||
Positive | Positive_clone | T22G5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (12) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |