WormBase Tree Display for Gene: WBGene00001501
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WBGene00001501 | SMap | S_parent | Sequence | D1037 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | ftn-2 | |||||||
Sequence_name | D1037.3 | ||||||||
Molecular_name | D1037.3 | ||||||||
D1037.3.1 | |||||||||
CE20622 | |||||||||
Other_name | CELE_D1037.3 | Accession_evidence | NDB | BX284601 | |||||
Public_name | ftn-2 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | ftn | ||||||||
Allele (16) | |||||||||
Strain | WBStrain00002965 | ||||||||
WBStrain00031408 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (17) | |||||||||
Ortholog (74) | |||||||||
Paralog | WBGene00001500 | Caenorhabditis elegans | From_analysis (4) | ||||||
Structured_description | Concise_description | ftn-2 encodes one of two C. elegans ferritin heavy chain homologs; loss of ftn-2 activity via deletion mutation results in slightly lower brood sizes and, under iron stress conditions, slightly faster growth from the L4 to adult stage of development, and slightly reduced lifespan; an ftn-2::gfp reporter fusion is expressed in diverse tissues, including the pharynx, intestine, and hypodermis, and its expression, along with that of ftn-2 mRNA, does not appear to change significantly under iron stress conditions. | Paper_evidence | WBPaper00005703 | |||||
WBPaper00006525 | |||||||||
WBPaper00024456 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson1823 | |||||||||
WBPerson567 | |||||||||
Date_last_updated | 10 Mar 2006 00:00:00 | ||||||||
Automated_description | Enables identical protein binding activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in cytoplasm. Expressed in body wall musculature and hypodermis. Human ortholog(s) of this gene implicated in several diseases, including hemochromatosis type 5; hyperferritinemia-cataract syndrome; and neurodegeneration with brain iron accumulation 3. Is an ortholog of human FTMT (ferritin mitochondrial). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0111256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) | ||||
DOID:1289 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) | ||||||
DOID:0111031 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3976) | ||||||
DOID:0080600 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3976,HGNC:3999) | ||||||
DOID:0110737 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) | ||||||
DOID:679 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3999) | ||||||
Molecular_info | Corresponding_CDS | D1037.3 | |||||||
Corresponding_transcript | D1037.3.1 | ||||||||
Other_sequence (155) | |||||||||
Associated_feature (16) | |||||||||
Experimental_info | RNAi_result (10) | ||||||||
Expr_pattern | Chronogram1229 | ||||||||
Expr3081 | |||||||||
Expr4744 | |||||||||
Expr5610 | |||||||||
Expr7855 | |||||||||
Expr1022759 | |||||||||
Expr1030901 | |||||||||
Expr1147349 | |||||||||
Expr2011914 | |||||||||
Expr2030151 | |||||||||
Drives_construct | WBCnstr00003471 | ||||||||
WBCnstr00009029 | |||||||||
WBCnstr00011121 | |||||||||
WBCnstr00012954 | |||||||||
WBCnstr00016205 | |||||||||
WBCnstr00036907 | |||||||||
Construct_product | WBCnstr00011121 | ||||||||
WBCnstr00036907 | |||||||||
Antibody | WBAntibody00002946 | ||||||||
Microarray_results (23) | |||||||||
Expression_cluster (215) | |||||||||
Interaction (202) | |||||||||
WBProcess | WBbiopr:00000039 | ||||||||
WBbiopr:00000096 | |||||||||
Map_info | Map | I | Position | -2.93309 | Error | 0.018064 | |||
Positive | Positive_clone | D1037 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4327 | |||||||
4429 | |||||||||
4670 | |||||||||
Pseudo_map_position | |||||||||
Reference (21) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |