WormBase Tree Display for Gene: WBGene00001491
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| WBGene00001491 | SMap | S_parent | Sequence | C24A11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | frm-4 | Person_evidence | WBPerson204 | |||||
| Sequence_name | C24A11.8 | ||||||||
| Molecular_name (11) | |||||||||
| Other_name | CELE_C24A11.8 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | frm-4 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | frm | ||||||||
| Allele (98) | |||||||||
| Strain | WBStrain00001366 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00022001 | ||||||||
| 00022002 | |||||||||
| 00022003 | |||||||||
| Ortholog (40) | |||||||||
| Paralog | WBGene00001488 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00001489 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001333 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | frm-4 encodes a predicted transmembrane protein that contains an N-terminal FERM (Band 4.1-ezrin-radixin-moesin) domain; by homology, FRM-4 is predicted to function as a membrane-cytoskeleton linker protein that plays a role in cell adhesion, migration, or organization of cell surface structures; however, as loss of frm-4 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of FRM-4 in C. elegans development and/or behavior is not yet known. | Paper_evidence | WBPaper00004402 | |||||
| WBPaper00004651 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in actomyosin structure organization. Predicted to be located in cytoskeleton. Expressed in PVDL; PVDR; head; and tail. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with eye movement abnormalities and ataxia. Is an ortholog of human FRMD3 (FERM domain containing 3) and FRMD5 (FERM domain containing 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0081275 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:28214) | ||||
| Molecular_info | Corresponding_CDS | C24A11.8a | |||||||
| C24A11.8b | |||||||||
| C24A11.8c | |||||||||
| Corresponding_transcript | C24A11.8a.1 | ||||||||
| C24A11.8a.2 | |||||||||
| C24A11.8b.1 | |||||||||
| C24A11.8b.2 | |||||||||
| C24A11.8c.1 | |||||||||
| Other_sequence (31) | |||||||||
| Associated_feature | WBsf716920 | ||||||||
| WBsf983685 | |||||||||
| WBsf983686 | |||||||||
| WBsf1009820 | |||||||||
| WBsf1009821 | |||||||||
| WBsf1009822 | |||||||||
| WBsf219419 | |||||||||
| WBsf219420 | |||||||||
| WBsf219421 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00002993 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00114829 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00029127 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002992 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116825 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00041048 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001501 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090549 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00117464 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002996 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1052 | ||||||||
| Expr5320 | |||||||||
| Expr5321 | |||||||||
| Expr11988 | |||||||||
| Expr1018021 | |||||||||
| Expr1030892 | |||||||||
| Expr1145087 | |||||||||
| Expr2011886 | |||||||||
| Expr2030124 | |||||||||
| Drives_construct | WBCnstr00002256 | ||||||||
| WBCnstr00004273 | |||||||||
| WBCnstr00036912 | |||||||||
| Construct_product | WBCnstr00036912 | ||||||||
| Microarray_results (33) | |||||||||
| Expression_cluster (142) | |||||||||
| Interaction (26) | |||||||||
| Map_info | Map | I | Position | -0.025651 | Error | 0.00187 | |||
| Positive | Positive_clone | C24A11 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00024261 | ||||||||
| WBPaper00031913 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064339 | |||||||||
| Remark | data submitted by [Gobel V] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
