WormBase Tree Display for Gene: WBGene00001442

WBGene00001442 SMap: S_parent: Sequence: C25A1
  Identity: Version: 1
    Name: CGC_name: fkh-10 Person_evidence: WBPerson411
      Sequence_name: C25A1.2
      Molecular_name: C25A1.2
        C25A1.2.1
        CE42739
      Other_name: CELE_C25A1.2 Accession_evidence: NDB BX284601
      Public_name: fkh-10
    DB_info: Database: AceView gene 1K740
        WormQTL gene WBGene00001442
        WormFlux gene WBGene00001442
        NDB locus_tag CELE_C25A1.2
        Panther gene CAEEL|WormBase=WBGene00001442|UniProtKB=O17593
          family PTHR11829
        NCBI gene 182874
        RefSeq protein NM_060275.7
        TrEMBL UniProtAcc O17593
        UniProt_GCRP UniProtAcc O17593
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fkh
    Allele (24)
    Strain: WBStrain00031597
      WBStrain00030057
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (41)
    Paralog: WBGene00001434 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001438 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001440 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001441 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003017 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003976 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00004013 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00002601 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00006853 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000912 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: fkh-10 encodes one of 15 forkhead transcriptional regulators encoded by the C. elegans genome; by homology, FKH-10 is predicted to function as a transcription factor that regulates gene expression during development; however, as loss of fkh-10 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of FKH-10 in C. elegans development and/or behavior is not yet known; nevertheless, reporter gene studies indicate that throughout larval and adult stages, fkh-10 expression is detected almost exclusively in six pairs of neuronal nuclei near the terminal bulb of the pharynx, suggesting that FKH-10 may have a specific function in neuronal differentiation. Paper_evidence: WBPaper00005730
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in gonad and pharyngeal neurons. Is an ortholog of human FOXL3 (forkhead box L3) and FOXL3-OT1. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C25A1.2
    Corresponding_CDS_history: C25A1.2:wp192
    Corresponding_transcript: C25A1.2.1
    Other_sequence: TSC02926_1
      Dviv_isotig27531
      TS00376
      Acan_isotig13569
      AE04819
      AYC03971_1
      JI210953.1
    Associated_feature: WBsf220199
    Gene_product_binds (373)
    Transcription_factor: WBTranscriptionFactor000173
  Experimental_info: RNAi_result: WBRNAi00112285 Inferred_automatically: RNAi_primary
      WBRNAi00114699 Inferred_automatically: RNAi_primary
      WBRNAi00092035 Inferred_automatically: RNAi_primary
      WBRNAi00113578 Inferred_automatically: RNAi_primary
      WBRNAi00022893 Inferred_automatically: RNAi_primary
      WBRNAi00114700 Inferred_automatically: RNAi_primary
      WBRNAi00112275 Inferred_automatically: RNAi_primary
      WBRNAi00003010 Inferred_automatically: RNAi_primary
      WBRNAi00041142 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2340
      Expr1013707
      Expr1145175
      Expr1200047
      Expr1200137
      Expr2011803
      Expr2030041
    Drives_construct: WBCnstr00010777
      WBCnstr00036944
    Construct_product: WBCnstr00016779
      WBCnstr00036944
    Microarray_results (18)
    Expression_cluster (85)
    Interaction (63)
  Map_info: Map: I Position: 4.71625 Error: 0.003634
    Positive: Positive_clone: C25A1 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4252
        4312
    Pseudo_map_position
  Reference: WBPaper00005730
    WBPaper00011551
    WBPaper00027309
    WBPaper00029337
    WBPaper00031320
    WBPaper00052328
    WBPaper00061738
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene