WormBase Tree Display for Gene: WBGene00001240
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WBGene00001240 | SMap | S_parent | Sequence | F11E6 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | elo | ||||||
Allele (25) | |||||||
Strain | WBStrain00049341 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (21) | |||||||
Ortholog (55) | |||||||
Paralog | WBGene00001239 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00001247 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00001242 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00001245 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00001244 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00001243 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00001246 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00001241 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
Structured_description | Concise_description | elo-2 encodes a palmitic acid elongase, homologous to polyunsaturated fatty acid (PUFA) elongases such as ELO-1, that is required for normally rapid growth, normally large body size, fertility, and for the quantitative regulation of the ultradian defecation rhythm; the joint action of ELO-2 with ELO-1 is strongly required for 20-carbon PUFA production and for general viability; loss of el-2 activity via RNAi also results in decreased intestinal dipeptide transport and increased fat droplet size; elo-2 is most strongly expressed in intestinal cells, as well as other tissues such as the ventral nerve cord, pharyngeal muscles, uterus, and tail. | Paper_evidence | WBPaper00004162 | |||
WBPaper00005654 | |||||||
WBPaper00005728 | |||||||
WBPaper00040287 | |||||||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Predicted to enable fatty acid elongase activity. Involved in several processes, including determination of adult lifespan; lipid metabolic process; and regulation of gene expression. Predicted to be located in membrane. Expressed in intestine; pharyngeal muscle cell; tail; uterus; and ventral nerve cord. Is an ortholog of human ELOVL3 (ELOVL fatty acid elongase 3) and ELOVL6 (ELOVL fatty acid elongase 6). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F11E6.5 | |||||
Corresponding_transcript | F11E6.5.1 | ||||||
Other_sequence (67) | |||||||
Associated_feature | WBsf652427 | ||||||
WBsf655542 | |||||||
WBsf978977 | |||||||
WBsf999043 | |||||||
Experimental_info | RNAi_result (30) | ||||||
Expr_pattern | Expr2433 | ||||||
Expr1028402 | |||||||
Expr1030786 | |||||||
Expr1148341 | |||||||
Expr2011279 | |||||||
Expr2029515 | |||||||
Drives_construct | WBCnstr00010825 | ||||||
WBCnstr00015807 | |||||||
WBCnstr00015808 | |||||||
WBCnstr00037019 | |||||||
Construct_product | WBCnstr00010825 | ||||||
WBCnstr00037019 | |||||||
Microarray_results (18) | |||||||
Expression_cluster (228) | |||||||
Interaction (41) | |||||||
Map_info | Map | IV | Position | 17.1016 | Error | 0.029226 | |
Positive | Positive_clone | F11E6 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4901 | |||||
4433 | |||||||
4778 | |||||||
Pseudo_map_position | |||||||
Reference (31) | |||||||
Picture | WBPicture0000013096 | ||||||
Remark | elo-2 was previously incorrectly connected to C40H1.4 [021023 ck1] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |