WormBase Tree Display for Gene: WBGene00001165
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WBGene00001165 | SMap | S_parent | Sequence | F56A11 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | efn | ||||||
Allele (170) | |||||||
Legacy_information | [C.elegansII] bx80sd : fusions among all rays; also head, body and (especially) tail deformities; bx80/+ impenetrant R4 to R3 transformation. [Chow and Emmons 1994; EM] | ||||||
Strain | WBStrain00005372 | ||||||
WBStrain00007176 | |||||||
WBStrain00049265 | |||||||
WBStrain00049276 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (33) | |||||||
Ortholog (50) | |||||||
Paralog | WBGene00001163 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00001164 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00006869 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
Structured_description | Concise_description | efn-4 encodes a divergent member of the ephrin family of ligands; efn-4 is required for neuroblast migrations during closure of the ventral gastrulation cleft and subsequent epidermal morphogenesis, possibly functioning independently of EFN-1, EFN-2, EFN-3, and the VAB-1 receptor during morphogenesis; EFN-4 can interact weakly with VAB-1 in vitro; EFN-4 is expressed in neural and epidermal precursors at the 100-cell stage, in head neurons, pharyngeal cells, lateral and tail neurons, and in the ectoderm during epidermal enclosure. | Paper_evidence | WBPaper00003865 | |||
WBPaper00005631 | |||||||
Curator_confirmed | WBPerson48 | ||||||
WBPerson1843 | |||||||
Date_last_updated | 23 Jul 2008 00:00:00 | ||||||
Automated_description | Predicted to enable ephrin receptor binding activity. Involved in several processes, including embryonic morphogenesis; nematode male tail tip morphogenesis; and regulation of axon guidance. Located in axon and neuronal cell body. Expressed in several structures, including CAN; epithelial cell; ganglia; intestinal cell; and somatic nervous system. Human ortholog(s) of this gene implicated in craniofrontonasal syndrome; dysostosis; and stomach cancer. Is an ortholog of human EFNB1 (ephrin B1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:1934 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3226) | ||
DOID:10534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3226) | ||||
DOID:14737 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3226) | ||||
Molecular_info | Corresponding_CDS | F56A11.3 | |||||
Corresponding_transcript | F56A11.3.1 | ||||||
Other_sequence | CR11929 | ||||||
TS00903 | |||||||
TSC03402_1 | |||||||
CRC05251_1 | |||||||
CBC06448_1 | |||||||
CR02130 | |||||||
Associated_feature (22) | |||||||
Experimental_info (9) | |||||||
Map_info | Map | IV | Position | -25.7615 | Error | 0.138637 | |
Positive | Positive_clone | F56A11 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 3132 | |||||
4992 | |||||||
5641 | |||||||
Reference (44) | |||||||
Method | Gene |