WormBase Tree Display for Gene: WBGene00000450
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WBGene00000450 | SMap | S_parent | Sequence | K03A11 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | ceh | ||||||
Allele (27) | |||||||
Strain | WBStrain00002444 | ||||||
WBStrain00001573 | |||||||
WBStrain00029949 | |||||||
WBStrain00032224 | |||||||
WBStrain00052007 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (24) | |||||||
Ortholog (29) | |||||||
Paralog | WBGene00000428 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00000430 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
WBGene00000434 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00000445 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000447 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000449 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00000463 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
WBGene00004011 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
WBGene00000584 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
Structured_description | Concise_description | ceh-28 encodes a homeodomain protein of the NK-2 family; ceh-28 is expressed in a single pharyngeal neuron, M4; within M4, CEH-28 functions to positively regulate the expression of dbl-1, which encodes a TGF-beta, and hence, TGF-beta signaling to ensure proper morphology of the pharyngeal g1 gland cells that are located adjacent to M4. | Paper_evidence | WBPaper00045065 | |||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson324 | |||||||
Date_last_updated | 09 Apr 2014 00:00:00 | ||||||
Automated_description | Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II and regulation of neuron differentiation. Part of chromatin. Expressed in several structures, including ABalaappa; ABalaappaa; ABalaappap; ABalapapa; and M4 neuron. Human ortholog(s) of this gene implicated in several diseases, including aortic valve disease 2; congenital heart disease (multiple); and heart conduction disease (multiple). Is an ortholog of human NKX2-5 (NK2 homeobox 5). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (11) | ||||||
Molecular_info | Corresponding_CDS | K03A11.3 | |||||
Corresponding_CDS_history | K03A11.3:wp101 | ||||||
K03A11.3:wp162 | |||||||
K03A11.3:wp190 | |||||||
Corresponding_transcript | K03A11.3.1 | ||||||
Other_sequence | WBC02282_1 | ||||||
CK854933.1 | |||||||
JI213807.1 | |||||||
Associated_feature | WBsf648642 | ||||||
WBsf663461 | |||||||
WBsf978476 | |||||||
Gene_product_binds | WBsf945412 | ||||||
WBsf945413 | |||||||
Transcription_factor | WBTranscriptionFactor000466 | ||||||
Experimental_info | RNAi_result | WBRNAi00049786 | Inferred_automatically | RNAi_primary | |||
WBRNAi00016509 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (13) | |||||||
Drives_construct | WBCnstr00000378 | ||||||
WBCnstr00002413 | |||||||
WBCnstr00004336 | |||||||
WBCnstr00007524 | |||||||
WBCnstr00007530 | |||||||
WBCnstr00012750 | |||||||
WBCnstr00037528 | |||||||
WBCnstr00042411 | |||||||
Construct_product | WBCnstr00016730 | ||||||
WBCnstr00037528 | |||||||
WBCnstr00042411 | |||||||
WBCnstr00042628 | |||||||
Microarray_results (19) | |||||||
Expression_cluster (35) | |||||||
Interaction (33) | |||||||
Product_binds_matrix | WBPmat00005550 | ||||||
Map_info | Map | X | Position | 10.2061 | Error | 0.074367 | |
Positive | Positive_clone | K03A11 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point (2) | ||||||
Pseudo_map_position | |||||||
Reference (19) | |||||||
Remark | Sequence From Thomas.Burglin@unibas.ch Wed Mar 7 09:49:40 2001 | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |