Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: RGD:620248

expand all nodes | collapse all nodes | view schema

Name Class

RGD:620248IdentityNameCGC_nameAbcb4Inferred_automaticallyAGR_import
Public_nameAbcb4
DB_infoDatabaseRGDid620248
AGRcURIRGD:620248
EnsEMBLENSEMBL_geneIDENSRNOG00000068001
ENSRNOG00000008012
UniProtUniProt_ACQ08201
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00003996Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Inparanoid
OMA
OrthoInspector
PhylomeDB
SonicParanoid
WBGene00003995Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
OMA
OrthoFinder
OrthoInspector
PhylomeDB
WBGene00004003Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
OMA
OrthoFinder
OrthoInspector
PhylomeDB
WBGene00003999Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
PhylomeDB
WBGene00004002Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
PhylomeDB
WBGene00004000Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
PhylomeDB
WBGene00003997Caenorhabditis elegansFrom_analysisOMA
OrthoFinder
PhylomeDB
WBGene00003998Caenorhabditis elegansFrom_analysisOMA
OrthoFinder
PhylomeDB
WBGene00004001Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
PhylomeDB
Structured_descriptionAutomated_descriptionPredicted to enable ATPase-coupled transmembrane transporter activity and phosphatidylcholine floppase activity. Involved in response to glucocorticoid and response to xenobiotic stimulus. Located in Golgi membrane and apical plasma membrane. Biomarker of cholestasis. Human ortholog(s) of this gene implicated in cholestasis (multiple) and liver cirrhosis (multiple). Orthologous to human ABCB4 (ATP binding cassette subfamily B member 4); PARTICIPATES IN multidrug resistance protein mediated transport pathway; bile acid transport pathway; INTERACTS WITH (+)-schisandrin B; 1,9-dideoxyforskolin; 1-naphthyl isothiocyanate.Inferred_automaticallyAGR_import