WormBase Tree Display for Gene: RGD:620248
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RGD:620248 | Identity | Name | CGC_name | Abcb4 | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Public_name | Abcb4 | |||||
DB_info | Database | RGD | id | 620248 | ||
AGR | cURI | RGD:620248 | ||||
EnsEMBL | ENSEMBL_geneID | ENSRNOG00000068001 | ||||
ENSRNOG00000008012 | ||||||
UniProt | UniProt_AC | Q08201 | ||||
Species | Rattus norvegicus | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00003996 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
Inparanoid | ||||||
OMA | ||||||
OrthoInspector | ||||||
PhylomeDB | ||||||
SonicParanoid | ||||||
WBGene00003995 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
Hieranoid | ||||||
OMA | ||||||
OrthoFinder | ||||||
OrthoInspector | ||||||
PhylomeDB | ||||||
WBGene00004003 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
Hieranoid | ||||||
OMA | ||||||
OrthoFinder | ||||||
OrthoInspector | ||||||
PhylomeDB | ||||||
WBGene00003999 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
OrthoFinder | ||||||
PhylomeDB | ||||||
WBGene00004002 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
OrthoFinder | ||||||
PhylomeDB | ||||||
WBGene00004000 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
OrthoFinder | ||||||
PhylomeDB | ||||||
WBGene00003997 | Caenorhabditis elegans | From_analysis | OMA | |||
OrthoFinder | ||||||
PhylomeDB | ||||||
WBGene00003998 | Caenorhabditis elegans | From_analysis | OMA | |||
OrthoFinder | ||||||
PhylomeDB | ||||||
WBGene00004001 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
OrthoFinder | ||||||
PhylomeDB | ||||||
Structured_description | Automated_description | Predicted to enable ATPase-coupled transmembrane transporter activity and phosphatidylcholine floppase activity. Involved in response to glucocorticoid and response to xenobiotic stimulus. Located in Golgi membrane and apical plasma membrane. Biomarker of cholestasis. Human ortholog(s) of this gene implicated in cholestasis (multiple) and liver cirrhosis (multiple). Orthologous to human ABCB4 (ATP binding cassette subfamily B member 4); PARTICIPATES IN multidrug resistance protein mediated transport pathway; bile acid transport pathway; INTERACTS WITH (+)-schisandrin B; 1,9-dideoxyforskolin; 1-naphthyl isothiocyanate. | Inferred_automatically | AGR_import |