Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: RGD:3318

expand all nodes | collapse all nodes | view schema

Name Class

RGD:3318IdentityNameCGC_nameAbcb1bInferred_automaticallyAGR_import
Public_nameAbcb1b
DB_infoDatabaseRGDid3318
AGRcURIRGD:3318
EnsEMBLENSEMBL_geneIDENSRNOG00000066042
ENSRNOG00000008012
UniProtUniProt_ACP43245
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00003996Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Inparanoid
OMA
OrthoInspector
PhylomeDB
SonicParanoid
WBGene00003995Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
OMA
OrthoFinder
OrthoInspector
PhylomeDB
WBGene00004003Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
OMA
OrthoFinder
OrthoInspector
PhylomeDB
WBGene00003999Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
PhylomeDB
WBGene00004002Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
PhylomeDB
WBGene00004000Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
PhylomeDB
WBGene00003997Caenorhabditis elegansFrom_analysisOMA
OrthoFinder
PhylomeDB
WBGene00003998Caenorhabditis elegansFrom_analysisOMA
OrthoFinder
PhylomeDB
WBGene00004001Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
PhylomeDB
Structured_descriptionAutomated_descriptionPredicted to enable floppase activity. Involved in several processes, including Sertoli cell barrier remodeling; cellular response to external biotic stimulus; and establishment of endothelial blood-brain barrier. Located in Golgi membrane and external side of apical plasma membrane. Used to study colorectal adenocarcinoma; end stage renal disease; epilepsy (multiple); high grade glioma; and human immunodeficiency virus infectious disease. Biomarker of brain disease (multiple); cholestasis; human immunodeficiency virus infectious disease; non-alcoholic fatty liver disease; and obstructive sleep apnea. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); human immunodeficiency virus infectious disease (multiple); inflammatory bowel disease (multiple); and leukemia (multiple). Orthologous to human ABCB1 (ATP binding cassette subfamily B member 1); PARTICIPATES IN bile acid transport pathway; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; 1,2-dimethylhydrazine.Inferred_automaticallyAGR_import