WormBase Tree Display for Gene: WBGene00006957
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WBGene00006957 | Evidence | Paper_evidence | WBPaper00005843 | ||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | C07G1 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | wsp-1 | Person_evidence | WBPerson633 | |||||
Sequence_name | C07G1.4 | ||||||||
Molecular_name | C07G1.4a | ||||||||
C07G1.4a.1 | |||||||||
CE32572 | |||||||||
C07G1.4b | |||||||||
CE32573 | |||||||||
C07G1.4b.1 | |||||||||
Other_name | CELE_C07G1.4 | Accession_evidence | NDB | BX284604 | |||||
Public_name | wsp-1 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:44 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | wsp | ||||||||
Allele (146) | |||||||||
Strain | WBStrain00002469 | ||||||||
WBStrain00028743 | |||||||||
WBStrain00007551 | |||||||||
WBStrain00007878 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (29) | |||||||||
Contained_in_operon | CEOP4274 | ||||||||
Ortholog (19) | |||||||||
Paralog | WBGene00015100 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Panther | |||||||||
WBGene00007840 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WBGene00020094 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00015107 | Caenorhabditis elegans | From_analysis | Panther | ||||||
Structured_description | Concise_description | wsp-1 encodes the C. elegans WASP ortholog; when mutated, human WASP leads to Wiskott-Aldrich syndrome (OMIM:301000); wsp-1 is required for hypodermal cell migration during morphogenesis (ventral enclosure); in a yeast two-hybrid assay WSP-1 physically interacts with WIP-1, the C. elegans WASP-interacting protein ortholog; WSP-1 and WIP-1 are mutually required for normal protein levels; WSP-1 is found in migrating hypodermal cells during ventral enclosure. | Paper_evidence | WBPaper00004103 | |||||
WBPaper00005843 | |||||||||
WBPaper00027006 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 29 May 2013 00:00:00 | ||||||||
Automated_description | Enables cytoskeletal regulatory protein binding activity and small GTPase binding activity. Involved in several processes, including embryonic morphogenesis; positive regulation of egg-laying behavior; and regulation of cellular component organization. Located in cell leading edge; cortical actin cytoskeleton; and presynaptic periactive zone. Expressed in Q cell; anchor cell; apoptotic cell; epithelial cell; and hypodermis. Is an ortholog of human WASL (WASP like actin nucleation promoting factor). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | C07G1.4a | |||||||
C07G1.4b | |||||||||
Corresponding_CDS_history | C07G1.4a:wp90 | ||||||||
C07G1.4b:wp90 | |||||||||
Corresponding_transcript | C07G1.4a.1 | ||||||||
C07G1.4b.1 | |||||||||
Other_sequence (30) | |||||||||
Associated_feature | WBsf668088 | ||||||||
WBsf668089 | |||||||||
WBsf668090 | |||||||||
WBsf668091 | |||||||||
WBsf668092 | |||||||||
WBsf997157 | |||||||||
WBsf997158 | |||||||||
WBsf1017812 | |||||||||
WBsf230394 | |||||||||
WBsf230395 | |||||||||
Experimental_info | RNAi_result (17) | ||||||||
Expr_pattern (13) | |||||||||
Drives_construct | WBCnstr00004412 | ||||||||
WBCnstr00022478 | |||||||||
WBCnstr00034071 | |||||||||
Construct_product (14) | |||||||||
Antibody | WBAntibody00000620 | ||||||||
WBAntibody00000753 | |||||||||
WBAntibody00000754 | |||||||||
Microarray_results (27) | |||||||||
Expression_cluster (105) | |||||||||
Interaction (128) | |||||||||
Map_info | Map | IV | Position | 3.65746 | Error | 0.002507 | |||
Positive | Positive_clone | C07G1 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4994 | |||||||
5010 | |||||||||
4600 | |||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00005843 | ||||||||
WBPaper00010071 | |||||||||
WBPaper00011962 | |||||||||
WBPaper00024256 | |||||||||
WBPaper00027006 | |||||||||
WBPaper00027244 | |||||||||
WBPaper00027296 | |||||||||
WBPaper00028087 | |||||||||
WBPaper00030279 | |||||||||
WBPaper00031082 | |||||||||
WBPaper00031546 | |||||||||
WBPaper00032090 | |||||||||
WBPaper00032405 | |||||||||
WBPaper00032783 | |||||||||
WBPaper00032907 | |||||||||
WBPaper00034074 | |||||||||
WBPaper00035252 | |||||||||
WBPaper00036309 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00038564 | |||||||||
WBPaper00038851 | |||||||||
WBPaper00039213 | |||||||||
WBPaper00039779 | |||||||||
WBPaper00040113 | |||||||||
WBPaper00040156 | |||||||||
WBPaper00040827 | |||||||||
WBPaper00040857 | |||||||||
WBPaper00042982 | |||||||||
WBPaper00043772 | |||||||||
WBPaper00048088 | |||||||||
WBPaper00048215 | |||||||||
WBPaper00048842 | |||||||||
WBPaper00049110 | |||||||||
WBPaper00049157 | |||||||||
WBPaper00049423 | |||||||||
WBPaper00050367 | |||||||||
WBPaper00051356 | |||||||||
WBPaper00052001 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00056797 | |||||||||
WBPaper00056964 | |||||||||
WBPaper00058353 | |||||||||
WBPaper00059924 | |||||||||
WBPaper00059953 | |||||||||
WBPaper00060014 | |||||||||
WBPaper00060679 | |||||||||
WBPaper00061198 | |||||||||
WBPaper00062488 | |||||||||
WBPaper00064401 | |||||||||
WBPaper00064588 | |||||||||
WBPaper00066364 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |