magu-2 encodes a protein with similarity to the MAGUK (membrane-associated guanylate kinase) family of proteins; loss of magu-2 activity in large-scale RNAi screens can result in embryonic lethality with low, reproducible chromosome segregation defects; magu-2 exhibits genetic interactions with sem-5 and glp-1.
Predicted to be involved in several processes, including establishment or maintenance of cell polarity; morphogenesis of an epithelial sheet; and protein localization to plasma membrane. Predicted to be located in adherens junction and plasma membrane. Expressed in head; hypodermis; and pharyngeal muscle cell. Is an ortholog of human PALS1 (protein associated with LIN7 1, MAGUK p55 family member).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.
CGC_data_submission
Moved tag-117 from magu-1 to magu-2 where it belongs, seems like a very old (2013) misassignment.