arg-1 encodes a member of the Delta/Serrate/LAG-2 family of transmembrane signaling ligands; arg-1 mediates cell fate decisions during early embryogenesis and in addition, is a downstream target of HLH-8/CeTwist, which binds E box sequences in the arg-1 promoter and is required for fate specification of a subset of mesodermal cells; arg-1 is closely related to apx-1 and lag-2 and is functionally interchangeable with them; an arg-1::gfp reporter is expressed in the vm1 vulval muscles, the intestinal, anal depressor, and anal sphincter muscles, and the head mesoderm cell.
Predicted to enable Notch binding activity. Predicted to be involved in cell communication. Predicted to be located in membrane. Expressed in several structures, including head mesodermal cell; male distal tip cell; non-striated muscle; somatic gonad precursor; and tail.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.