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WormBase Tree Display for Gene: WBGene00011232

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Name Class

WBGene00011232SMapS_parentSequenceR11A5
IdentityVersion2
NameCGC_namepck-2Person_evidenceWBPerson2192
Sequence_nameR11A5.4
Molecular_name (13)
Other_nameCELE_R11A5.4Accession_evidenceNDBBX284601
Public_namepck-2
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
217 Feb 2012 16:57:01WBPerson2970Name_changeCGC_namepck-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpck
Allele (66)
Possibly_affected_byWBVar02153165
StrainWBStrain00002263
WBStrain00032650
WBStrain00049322
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (45)
ParalogWBGene00021043Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00019151Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionpck-2 is one of three C. elegans genes that encode proteins with similarity to phosphoenolpyruvate carboxykinase (PEPCK); by similarity, the products of pck-2 are predicted to function in gluconeogenesis.Curator_confirmedWBPerson1843
Date_last_updated02 Aug 2011 00:00:00
Automated_descriptionPredicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including carbohydrate biosynthetic process; cellular response to oxygen-containing compound; and propionate catabolic process. Predicted to be located in cytosol and mitochondrion. Expressed in several structures, including body wall musculature; hypodermis; muscle cell; pharynx; and in male. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Is an ortholog of human PCK1 (phosphoenolpyruvate carboxykinase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8724)
DOID:9352Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8724)
Molecular_infoCorresponding_CDSR11A5.4a
R11A5.4b
R11A5.4c
R11A5.4d
Corresponding_CDS_historyR11A5.4b:wp274
Corresponding_transcriptR11A5.4a.1
R11A5.4a.2
R11A5.4b.1
R11A5.4c.1
R11A5.4d.1
Other_sequenceNB08103
ES411655.1
BU089024.1
ASC32153_1
FF678370.1
FC814720.1
HCC09775_1
FK804294.1
FG977840.1
HG00407
AE04370
BXC07656_1
BUC00735_1
OVC02764_1
Tcol_isotig06776
CR11680
FG971940.1
DA00450
Dviv_isotig12756
CK850571.1
JI474157.1
JI461855.1
HG09561
EX914989.1
JI480183.1
FK800352.1
RS06540
FK800876.1
EX551310.1
CJC00862_1
TSC02629_1
JI181359.1
ES412282.1
FC809435.1
HC03259
AS08262
BXC07283_1
FC554141.1
JI470621.1
FE910459.1
FG980423.1
JI475900.1
FG979302.1
CRC00774_2
ES566914.1
ES563501.1
HC05579
FG978137.1
FC548879.1
FG971470.1
FG971208.1
BXC00981_1
FK808051.1
AAC00352_1
CR02305
FK805449.1
HS00856
EX916327.1
BXC04284_1
ES743161.1
BU088612.1
EX565881.1
ACC05628_1
EX913608.1
EX910824.1
HCC00038_1
JI171753.1
ES291068.1
FG975280.1
FK800393.1
CGC01529_1
ASC01717_1
FC549539.1
JI168869.1
MI03895
EX015268.1
EX561118.1
FK802674.1
HC01262
CR10347
GO254922.1
TSC01599_1
AM743222.1
DVC01363_1
FK806640.1
DVC02959_1
OF01365
AM157847.1
JI470262.1
FG978446.1
JO470498.1
BU087295.1
FK807658.1
FK802049.1
MIC00315_1
ODC00156_1
JO473635.1
ES563267.1
GT737991.1
CR06829
EV851138.1
FK804868.1
SSC02691_1
FK800021.1
MHC05698_1
FF680786.1
AS00092
FK803693.1
EX549803.1
HBC19191_1
GRC01948_1
EX559111.1
JI167559.1
NBC00508_1
Tcol_isotig06774
JI168340.1
Hbac_isotig01091
JI463670.1
RS09070
HBC02841_1
NBC00528_1
MI00479
XI05220
CBC06143_1
MA01273
FK805725.1
FE909801.1
EX910474.1
FK807476.1
FF680743.1
FG976337.1
FK805347.1
JI169505.1
FE914233.1
FG971832.1
AI438246.1
ASC00256_1
AYC01641_1
EX007109.1
CK850851.1
MHC01756_1
HGC05624_1
BI772979.1
CGC00844_1
FF681365.1
FC543851.1
CR07503
GO250634.1
JI481285.1
EX549070.1
Tcir_isotig14227
FG973006.1
AS02953
BI772933.1
AM157849.1
FK806292.1
AS15062
ACC39754_1
FG976926.1
JI465207.1
AIC00137_1
PPC03348_1
SR01315
EX013196.1
JI168449.1
CBC00379_1
ASC39657_1
CR06921
HG09575
Oden_isotig17816
FK805669.1
CRC01709_1
HCC02378_1
CGC00457_1
FK809123.1
FK802278.1
EX544998.1
HO348278.1
FE909281.1
JI460098.1
FF679058.1
JI467360.1
CK850668.1
FC540653.1
ES411946.1
EH005429.1
WBC01926_1
MI00942
AE00812
EV853202.1
GO239512.1
HC05756
FK800734.1
FK805079.1
FK801112.1
FK801008.1
CBC00672_1
AS01910
FC539135.1
JI481714.1
Tcol_isotig06773
ES410027.1
Dviv_isotig12757
BUC00442_1
EX916634.1
EX910102.1
GR12884
DAC00691_1
HBC00448_1
FK805610.1
FF681688.1
MI03664
FK808338.1
FK800307.1
FF678579.1
HC02814
CRC00774_1
Oden_isotig23091
TCC01317_1
JI168278.1
BI772927.1
FG974801.1
MI02415
EX013374.1
ES739412.1
RSC01648_1
MH02352
DN190595.1
AM157850.1
ODC00113_1
GO239135.1
OFC00899_1
HGC00028_1
TMC01074_1
CR11161
CR02745
FG974112.1
AE04800
FK799915.1
GO254861.1
FF678808.1
HC05980
JO468034.1
HC05458
CJC03385_1
HC04669
FF681653.1
FF679072.1
XI01380
FK805828.1
SS00905
EX014217.1
FG972769.1
NAC00300_1
EX545446.1
FG980616.1
FK809560.1
MC00216
AM157854.1
EX916376.1
FE910367.1
JI481771.1
JI463995.1
ES567152.1
JI168401.1
FF678498.1
JI469606.1
MCC00769_1
AM157851.1
FG974741.1
JO475330.1
FK809520.1
GE626551.1
Acan_isotig09968
FF681094.1
Acan_isotig09452
FC541505.1
SRC00223_1
FK809064.1
ASC07299_1
Tcol_isotig06775
EX547745.1
TSC11846_1
AS00807
FF678156.1
AE04509
FC555001.1
BU666100.1
CBC12853_1
JI475073.1
MIC00981_1
NAC01673_1
JI465555.1
FG980313.1
MH07028
FK802379.1
JI481499.1
NB08162
EX554895.1
RSC03560_1
FF678690.1
FK803224.1
EX914881.1
FK807004.1
Dviv_isotig12755
MI04457
OOC00595_1
TDC03079_1
HC03219
MI04253
DA05512
FK808322.1
FK805628.1
MH01731
ODC00002_1
EX559563.1
NB08116
JI178854.1
EY460702.1
CJC06640_1
JI168904.1
ES739007.1
CRC06563_1
FK807377.1
AM157848.1
XIC01575_1
FE914513.1
BM277128.1
GO254729.1
EE724187.1
JI464834.1
ES584533.1
FE913553.1
JO472889.1
Tcir_isotig05874
CJC00181_1
FC542000.1
Acan_isotig13791
FE910559.1
XIC00014_1
TX00117
ACC06920_1
FK800067.1
FG973285.1
ASC00355_1
ASC15911_1
BMC01320_1
SS00714
EX009676.1
XI01268
FG974903.1
XIC00211_1
HSC01163_1
BG467485.1
AM157853.1
JI168042.1
ES740586.1
ACC09095_1
WBC01989_1
Associated_feature (19)
Experimental_infoRNAi_resultWBRNAi00116976Inferred_automaticallyRNAi_primary
WBRNAi00051760Inferred_automaticallyRNAi_primary
WBRNAi00077181Inferred_automaticallyRNAi_primary
WBRNAi00090555Inferred_automaticallyRNAi_primary
WBRNAi00034849Inferred_automaticallyRNAi_primary
WBRNAi00001222Inferred_automaticallyRNAi_primary
WBRNAi00051759Inferred_automaticallyRNAi_primary
WBRNAi00004079Inferred_automaticallyRNAi_primary
Expr_pattern (16)
Drives_constructWBCnstr00002285
WBCnstr00004292
WBCnstr00004926
WBCnstr00011844
WBCnstr00030823
WBCnstr00042040
WBCnstr00042041
Construct_productWBCnstr00030823
WBCnstr00042040
Microarray_results (41)
Expression_cluster (246)
Interaction (47)
Map_info (3)
Reference (22)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
[200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (2.36373)
MethodGene