WormBase Tree Display for Gene: WBGene00001394

WBGene00001394 SMap: S_parent: Sequence: W02A2
  Identity: Version: 1
    Name: CGC_name: fat-2
      Sequence_name: W02A2.1
      Molecular_name: W02A2.1a
        W02A2.1a.1
        CE21231
        W02A2.1b
        CE49971
        W02A2.1b.1
      Other_name: CELE_W02A2.1 Accession_evidence: NDB BX284604
      Public_name: fat-2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fat
    Allele (35)
    Strain: WBStrain00031679
      WBStrain00004011
    RNASeq_FPKM (74)
    GO_annotation (22)
    Ortholog (32)
    Paralog: WBGene00001393 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: fat-2 encodes a delta-12 fatty acyl desaturase that increases membranefluidity when expressed in yeast, and that may protect against coldstress; FAT-2's substrate is unknown, but may be acyl-CoA; FAT-2 isrequired in vivo for normal levels of C18 or C20 polyunsaturated fattyacids (PUFAs); FAT-2 is fully required for a sperm-attracting cue(perhaps an eicosanoid) secreted by oocytes, and partially required forthe polarizing activity of PAR-3, PAR-6, and other proteins; FAT-2 isalso required for a normally fast growth rate and movement rate, and fornormal body shape, defecation rhythm, and brood size; when expressed in yeast, FAT-2 exhibits a v+3 mode of desaturase activity, catalyzing double bond formation three carbons from an existing double bond. Paper_evidence (8)
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 10 Jun 2010 00:00:00
      Automated_description: Enables stearoyl-CoA 9-desaturase activity. Involved in several processes, including collagen and cuticulin-based cuticle development; fatty acid biosynthetic process; and innate immune response. Predicted to be located in membrane. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: W02A2.1a
      W02A2.1b
    Corresponding_transcript: W02A2.1a.1
      W02A2.1b.1
    Other_sequence: AF240777
      BMC04890_1
      Oden_isotig07223
      CSC01834_1
      FC541408.1
      PPC07094_1
      MP01080
      ASC38390_1
      SR01681
      FC546661.1
      EW742439.1
      MIC00918_1
      FG973243.1
      FG973206.1
      FG978033.1
      BM00904
      Hbac_isotig01505
      FG970833.1
      ES739012.1
      CBC15865_1
      FG971620.1
      FG979086.1
      FK800795.1
      FF678712.1
      BXC00929_1
      FG971755.1
      ES744357.1
      FF680938.1
      PPC01401_1
      CRC03723_1
      JI477429.1
      FG975999.1
      FG974412.1
      FG972696.1
      Oden_isotig07219
      FF681518.1
      FG975322.1
      FE912852.1
      CR10415
      EX545571.1
      FF681039.1
      FG978966.1
      Dviv_isotig23322
      BUC01607_1
      EX550097.1
      HBC00144_1
      ACC14112_1
      FG973672.1
      JI482353.1
      Tcol_isotig06212
      EX550468.1
      FG979147.1
      FG619064.1
      EX556754.1
      SSC02654_1
      FG974925.1
      Oden_isotig07222
      SCC00010_1
      FG970705.1
      WBC01758_1
      FG974748.1
      JI169968.1
      Oden_isotig07221
      BMC02897_1
      EX910031.1
      HBC02411_1
      CR01659
      FG980220.1
      HBC17200_1
      FG975911.1
      FG971932.1
      EG025388.1
      Acan_isotig01020
      ACC39114_1
      FG975417.1
      FC809879.1
      ES411366.1
      FC547868.1
      AM744195.1
      CR09659
      EX567070.1
      FG976550.1
      TDC02917_1
      FF681418.1
      Acan_isotig01019
      MH05210
      GE626292.1
      TDC02301_1
      FK807455.1
      EX542106.1
      EX558112.1
      FG979707.1
      FG975032.1
      MHC01762_1
      FD514838.1
      FG975490.1
      CR09272
      SRC00496_1
      CR00369
      Tcir_isotig31271
      PT02869
      FG977426.1
      FK804227.1
      FG974561.1
      Oden_isotig07218
      FG970837.1
      BG734376.1
      FG971385.1
      FC547262.1
      CBC02475_2
      HGC00553_1
      JI469582.1
      FG980814.1
      CK850293.1
      FG977409.1
      EX014094.1
      EX542903.1
      EW742174.1
      CJC00531_1
      CJC00399_1
      FG978312.1
      MI00103
      FG971775.1
      CBC02475_1
      OOC02616_1
      AM743450.1
      FG978902.1
      FG976640.1
      FG975267.1
      FG972278.1
      EX541807.1
      BXC02228_1
      PP02295
      Name_isotig03616
      FC815239.1
      EX911125.1
      PPC05485_1
      FG976058.1
      ACC06494_1
      Tcol_isotig06213
      DR120996.1
      CBC01090_1
      HG03344
      Tcir_isotig08251
      HGC11725_1
      FG977053.1
      SS01248
      Oden_isotig07220
      Tcol_isotig06211
      FG980159.1
      ACC02039_1
      FG973673.1
      FG980872.1
    Associated_feature: WBsf660885
      WBsf979037
      WBsf998380
      WBsf998381
      WBsf1018513
      WBsf229419
  Experimental_info: RNAi_result (19)
    Expr_pattern (7)
    Drives_construct: WBCnstr00003419
      WBCnstr00036975
    Construct_product: WBCnstr00036975
    Microarray_results (19)
    Expression_cluster (258)
    Interaction (211)
    WBProcess: WBbiopr:00000121
  Map_info: Map: IV Position: 8.52821 Error: 0.001854
    Positive: Positive_clone: W02A2 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4297
        4298
    Pseudo_map_position
  Reference (56)
  Remark: M03A8.1 link removed by agreement. [sdm 0107]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene