WormBase Tree Display for Gene: WBGene00010988

WBGene00010988 SMap: S_parent: Sequence: R03D7
  Identity: Version: 2
    Name: CGC_name: metr-1 Person_evidence: WBPerson1711
      Sequence_name: R03D7.1
      Molecular_name: R03D7.1
        R03D7.1.1
        CE01609
      Other_name: CELE_R03D7.1 Accession_evidence: NDB BX284602
      Public_name: metr-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:52 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 20 Apr 2011 10:05:24 WBPerson2970 Name_change: CGC_name: metr-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: metr
    Allele (55)
    Strain: WBStrain00001842
      WBStrain00002165
      WBStrain00031469
    RNASeq_FPKM (74)
    GO_annotation (23)
    Ortholog: WBGene00057520 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00039583 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            WormBase-Compara
      WBGene00149483 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00160142 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      CSP21.g5982 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g16531 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP26.g18248 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g16825 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g1056 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP29.g17167 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g20296 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g10976 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g7287 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g4896 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g5074 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00039.g2161 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_00039.g2162 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_00039.g2163 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_05108.g19357 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-metr-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g11267 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00184.g6524 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_05914 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_005863 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g02524 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g17827 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_20079800 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g5844 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00176475 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00208117 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00114809 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00264576 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00297032 Trichuris muris From_analysis: WormBase-Compara
      WBGene00297737 Trichuris muris From_analysis: WormBase-Compara
      WBGene00301311 Trichuris muris From_analysis: WormBase-Compara
      ZFIN:ZDB-GENE-031001-5 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:7468 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:894292 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:621283 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00015512 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00020491 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: metr-1 encodes a protein orthologous to the human gene Methionine synthase (MTR), which is involved in the conversion of homocysteine to form methionine. Paper_evidence: WBPaper00042203
          Curator_confirmed: WBPerson324
            WBPerson1823
            WBPerson567
          Date_last_updated: 07 May 2013 00:00:00
      Automated_description: Predicted to enable methionine synthase activity. Predicted to be involved in homocysteine metabolic process; methionine biosynthetic process; and tetrahydrofolate metabolic process. Predicted to be located in cytosol. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; and hematologic cancer (multiple). Is an ortholog of human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:9352 Homo sapiens Paper_evidence: WBPaper00042203
          Curator_confirmed: WBPerson324
          Date_last_updated: 13 Mar 2023 00:00:00
    Potential_model (14)
  Models_disease_asserted: WBDOannot00000175
  Molecular_info: Corresponding_CDS: R03D7.1
    Corresponding_transcript: R03D7.1.1
    Other_sequence (51)
    Associated_feature: WBsf222084
      WBsf222085
  Experimental_info: RNAi_result: WBRNAi00071221 Inferred_automatically: RNAi_primary
      WBRNAi00034551 Inferred_automatically: RNAi_primary
      WBRNAi00090587 Inferred_automatically: RNAi_primary
      WBRNAi00051170 Inferred_automatically: RNAi_primary
      WBRNAi00106971 Inferred_automatically: RNAi_primary
      WBRNAi00017346 Inferred_automatically: RNAi_primary
    Expr_pattern (9)
    Drives_construct: WBCnstr00002636
      WBCnstr00004383
    Regulate_expr_cluster: WBPaper00060951:metr-1(os521)_downregulated
      WBPaper00060951:metr-1(os521)_upregulated
    Microarray_results (20)
    Expression_cluster (213)
    Interaction (110)
  Map_info (3)
  Reference (25)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene