| | | See also n490, n506, n785, n786, n787, n788, n795, n796, n797, n798, n799, n801, n802, n803, n804, n805, n806, n807, n808, n809, n810, n811, n812, n813, n814, n815, n816, n817, n818, n819, n820 |
| | | [C.elegansII] n490sd : small, hypercontracted, rigid paralytic; very poor growth; abnormal muscle structure. Muscle hyperactivated, sticky pumping, short.n490/+ similar but less severe phenotype. Probable neomorphic gf allele. Suppressed by mutations in unc-15, unc-22, unc-45, unc-54etc. See also sup-20.ES3. OA2 (gf): n506 (less severe; ME0), n1274. Also intragenic revertants: n490n804 (WT, no behavioral or muscular abnormality; probable null phenotype), n490n820 etc. OA>10 (ird). Cloned: encodes degenerin family member,related to amiloride-sensitive Na channels. [Park and Horvitz 1986b; MT; RW] |