WormBase Tree Display for Gene: WBGene00002987

WBGene00002987 SMap: S_parent: Sequence: ZC64
  Identity: Version: 2
    Name: CGC_name: lim-4 Person_evidence: WBPerson545
      Sequence_name: ZC64.4
      Molecular_name: ZC64.4a
        ZC64.4a.1
        CE25675
        ZC64.4b
        CE51976
        ZC64.4c
        CE52031
        ZC64.4b.1
        ZC64.4c.1
      Other_name: nss-1 Paper_evidence: WBPaper00026818
        CELE_ZC64.4 Accession_evidence: NDB BX284606
      Public_name: lim-4
    DB_info: Database: AceView gene XE490
        WormQTL gene WBGene00002987
        WormFlux gene WBGene00002987
        NDB locus_tag CELE_ZC64.4
        Panther gene CAEEL|WormBase=WBGene00002987|UniProtKB=G5EEA1
          family PTHR24208
        NCBI gene 180672
        RefSeq protein NM_076268.2
            NM_001351878.2
            NM_001351879.2
        SwissProt UniProtAcc G5EEA1
        UniProt_GCRP UniProtAcc G5EEA1
    Species: Caenorhabditis elegans
    History: Version_change (2)
      Acquires_merge: WBGene00003820
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lim
    Allele (81)
    Strain: WBStrain00001913
      WBStrain00023455
      WBStrain00029156
      WBStrain00005258
      WBStrain00049271
    In_cluster: conserved_RDE-1_cluster
    RNASeq_FPKM (74)
    GO_annotation (24)
    Ortholog: WBGene00051912 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00034847 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00120288 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00227603 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g2483 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g3313 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g12595 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g10413 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g459 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g23296 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g359 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g20491 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g26580 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g22445 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00457.g11076 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-lim-4 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g18236 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00003.g236 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_00761 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_024170 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g13527 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g1562 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_X0264100 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrX_pilon.g18830 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00238705 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00203796 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00255929 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00292218 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0013751 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-031008-2 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-041025-1 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-060531-41 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:21735 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:28838 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1306803 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1096343 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1306174 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1308749 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00000438 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00003167 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00003000 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00006654 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00002989 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00002988 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00006824 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00015216 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00017644 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00022518 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: lim-4 encodes a LIM homeodomain protein homologous to murine Lhx6 and L3/Lhx7, and to Drosophila ARROWHEAD; LIM-4 is required for differentiation of AWB chemosensory neurons, for several but not all aspects of RID motor neuron differentiation, expression of ser-2, repulsion from chemosensory repellants, SAA neurite outgrowth, and normal locomotion and head foraging; lim-4 is expressed in AWB, RID, RIV, RMDL, RMDR, RMEV, four SAA neurons, and four SIA neurons. Paper_evidence: WBPaper00003593
            WBPaper00006180
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell differentiation; positive regulation of transcription by RNA polymerase II; and serotonin biosynthetic process. Located in nucleus. Expressed in several structures, including ABalpppppa; head muscle; head neurons; lumbar neurons; and somatic nervous system. Is an ortholog of human LHX6 (LIM homeobox 6) and LHX8 (LIM homeobox 8). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZC64.4a
      ZC64.4b
      ZC64.4c
    Corresponding_transcript: ZC64.4a.1
      ZC64.4b.1
      ZC64.4c.1
    Other_sequence (14)
    Associated_feature: WBsf653872
      WBsf670378
      WBsf670379
      WBsf978715
      WBsf1004755
      WBsf237227
      WBsf237228
    Gene_product_binds: WBsf979152
      WBsf979153
      WBsf979156
    Transcription_factor: WBTranscriptionFactor000525
  Experimental_info: RNAi_result: WBRNAi00093991 Inferred_automatically: RNAi_primary
      WBRNAi00021755 Inferred_automatically: RNAi_primary
      WBRNAi00059017 Inferred_automatically: RNAi_primary
    Expr_pattern (16)
    Drives_construct: WBCnstr00000961
      WBCnstr00001663
      WBCnstr00002702
      WBCnstr00005147
      WBCnstr00006276
      WBCnstr00006356
      WBCnstr00012900
      WBCnstr00036303
    Construct_product: WBCnstr00000961
      WBCnstr00005147
      WBCnstr00036303
      WBCnstr00038818
    Microarray_results (18)
    Expression_cluster (135)
    Interaction (81)
  Map_info: Map: X Position: -9.21387 Error: 0.024615
    Positive: Positive_clone: ZC64 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4205
        4476
    Pseudo_map_position
  Reference (64)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene