WormBase Tree Display for Gene: WBGene00000465

WBGene00000465 SMap: S_parent: Sequence: C07G2
  Identity: Version: 3
    Name: CGC_name: cpg-1 Paper_evidence: WBPaper00027679
      Sequence_name: C07G2.1
      Molecular_name: C07G2.1a
        C07G2.1a.1
        CE00665
        C07G2.1b
        CE33971
        C07G2.1b.1
      Other_name: cej-1
        CELE_C07G2.1 Accession_evidence: NDB BX284603
      Public_name: cpg-1
    DB_info: Database: AceView gene 3F579
        WormQTL gene WBGene00000465
        WormFlux gene WBGene00000465
        NDB locus_tag CELE_C07G2.1
        Panther gene CAEEL|WormBase=WBGene00000465|UniProtKB=Q17802
          family PTHR23301
        NCBI gene 175586
        RefSeq protein NM_001025989.5
            NM_001025988.8
        SwissProt UniProtAcc Q17802
        TREEFAM TREEFAM_ID TF316636
        UniProt_GCRP UniProtAcc Q17802
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 16 Jun 2006 15:10:10 WBPerson2970 Name_change: Other_name: cpg-1
        3 14 Jan 2008 11:23:07 WBPerson2970 Name_change: CGC_name: cej-1 -> cpg-1
                Other_name: cej-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cpg
    Allele (40)
    Strain: WBStrain00032264
      WBStrain00032265
      WBStrain00005743
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog: WBGene00071112 Caenorhabditis remanei From_analysis: OrthoMCL
            OMA
            WormBase-Compara
      WBGene00026714 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00151774 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00066726 Caenorhabditis remanei From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00140379 Caenorhabditis brenneri From_analysis: OMA
            WormBase-Compara
      WBGene00146195 Caenorhabditis brenneri From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00148621 Caenorhabditis brenneri From_analysis: OMA
            WormBase-Compara
      WBGene00121554 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00119587 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      CBOVI.g8217 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g5899 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP21.g5900 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g21300 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP31.g17501 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP38.g21930 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g9940 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP40.g4925 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00500.g11591 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-cpg-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g12630 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00303.g9036 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_04941 Caenorhabditis latens From_analysis: WormBase-Compara
      FL83_17710 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_002899 Caenorhabditis remanei From_analysis: WormBase-Compara
      GCK72_002971 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g02277 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_10292100 Caenorhabditis inopinata From_analysis: WormBase-Compara
      Sp34_10292300 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g7463 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00121622 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00210548 Caenorhabditis japonica From_analysis: WormBase-Compara
      FB:FBgn0031097 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0022770 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0031737 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0027600 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0052302 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0036220 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0036225 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0036228 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0036361 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0036362 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0036940 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0036948 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0036949 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0036950 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0036951 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0036952 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0036953 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0260393 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0026077 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
    Paralog: WBGene00015102 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00019833 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016534 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00010351 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00021005 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: cpg-1 encodes, by alternative splicing, two isoforms of a chondroitin proteoglycan; CPG-1 contains three chitin-binding peritrophin-A domains and two mucin-like regions; CPG-1 is individually dispensable for normal embryonic development; however, CPG-1 and CPG-2 are jointly required for osmotic integrity of early embryos, error-free chromosomal segregation during meiosis, polar body extrusion, association of the sperm pronucleus/centrosome complex (SPCC) with the early embryonic cortex, localization of PAR-2 in early embryos, posterior localization of P granules or PIE-1, and pseudocleavage; CPG-1, like CPG-2, is covalently linked to chondroitin, which itself is required for vulval morphogenesis, polar-body extrusion, and separation of the eggshell from the embryonic plasma membrane; cpg-1 mRNA, like that of cpg-2, is expressed specifically in the adult hermaphrodite germ line and is bound by GLD-1; CPG-1 has five potential chondroitin attachment sites, one of them verified by mass spectrometry, and transgenic CPG-1 synthesized in mammalian cells carries chondroitin sulfate chains; CPG-1's multiple peritrophin-A domains may enable mechanical cross-linking of chitin. Paper_evidence (9)
          Curator_confirmed: WBPerson567
          Date_last_updated: 09 Apr 2007 00:00:00
      Automated_description: Enables chitin binding activity. Involved in several processes, including eggshell formation; mitotic cytokinesis; and regulation of cytokinesis. Located in external encapsulating structure. Expressed in eggshell; germ line; and oocyte. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C07G2.1a
      C07G2.1b
    Corresponding_transcript: C07G2.1a.1
      C07G2.1b.1
    Other_sequence (49)
    Associated_feature: WBsf019203
      WBsf645094
      WBsf976109
      WBsf976110
      WBsf992144
      WBsf992145
      WBsf1014761
      WBsf1014762
      WBsf224744
  Experimental_info: RNAi_result: WBRNAi00078684 Inferred_automatically: RNAi_primary
      WBRNAi00040019 Inferred_automatically: RNAi_primary
      WBRNAi00000152 Inferred_automatically: RNAi_primary
      WBRNAi00022636 Inferred_automatically: RNAi_primary
      WBRNAi00092482 Inferred_automatically: RNAi_primary
      WBRNAi00007842 Inferred_automatically: RNAi_primary
      WBRNAi00005076 Inferred_automatically: RNAi_primary
      WBRNAi00028645 Inferred_automatically: RNAi_primary
      WBRNAi00010402 Inferred_automatically: RNAi_primary
      WBRNAi00092494 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2109
      Expr4104
      Expr13068
      Expr13388
      Expr1023887
      Expr1030269
      Expr1144095
      Expr2010482
      Expr2028722
    Drives_construct: WBCnstr00015402
      WBCnstr00037990
    Construct_product: WBCnstr00015402
      WBCnstr00037990
    Microarray_results (31)
    Expression_cluster (269)
    Interaction (213)
  Map_info: Map: III Position: -3.15507 Error: 0.001827
    Positive: Positive_clone: C07G2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (19)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene