WormBase Tree Display for Gene: WBGene00003864

WBGene00003864 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 1
    Name: CGC_name: oma-1 Person_evidence: WBPerson374
      Sequence_name: C09G9.6
      Molecular_name: C09G9.6
        C09G9.6.1
        CE03005
      Other_name: moe-1
        CELE_C09G9.6 Accession_evidence: NDB BX284604
      Public_name: oma-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: oma
    Allele (56)
    Strain: WBStrain00035069
      WBStrain00035066
      WBStrain00035067
      WBStrain00035068
      WBStrain00040433
      WBStrain00040434
      WBStrain00048324
      WBStrain00052677
    RNASeq_FPKM (74)
    GO_annotation (55)
    Contained_in_operon: CEOP4312
    Ortholog: WBGene00040414 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            WormBase-Compara
      WBGene00077396 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00127384 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00061597 Caenorhabditis remanei From_analysis: TreeFam
            WormBase-Compara
      WBGene00121093 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00193151 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00064784 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00141052 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00127525 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00107947 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00227668 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g12873 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g10034 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g20361 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP26.g20725 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g12512 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g7932 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g27325 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g12756 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP32.g12759 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP32.g5337 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g9207 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g3719 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g22195 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      CSP40.g3251 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00579.g12424 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_12481.g23779 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_IV.g13103 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g15223 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01285.g19860 Caenorhabditis sinica From_analysis: WormBase-Compara
      Csp5_scaffold_02281.g25782 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_19900 Caenorhabditis latens From_analysis: WormBase-Compara
      FL83_24769 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_008852 Caenorhabditis remanei From_analysis: WormBase-Compara
      GCK72_008974 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g02665 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g2109 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40348000 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g11189 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00246572 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00266462 Strongyloides ratti From_analysis: WormBase-Compara
      SGD:S000004126 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Panther
            SonicParanoid
      SGD:S000002558 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Panther
            SonicParanoid
      FB:FBgn0011837 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            Panther
      ZFIN:ZDB-GENE-990806-20 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
      HGNC:1107 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
      HGNC:1108 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
      MGI:99180 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
            PhylomeDB
            SonicParanoid
      RGD:62009 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
            SonicParanoid
      RGD:620722 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1308913 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            Panther
            SonicParanoid
    Paralog (20)
    Structured_description: Concise_description: oma-1 encodes a zinc finger protein of the TIS11 finger type that is paralogous to OMA-2; while either oma-1 or oma-2 individually have no obvious mutant phenotype, oma-1 and oma-2 doubly mutant animals show defects in oocyte maturation, indicating that the two genes function redundantly in this process; whereas normal oocytes are released from meiotic prophase I arrest during oocyte maturation, oma-1;oma-2 mutant oocytes initiate, but fail to complete, maturation, arresting at a defined point in meiotic prophase I; the meiotic arrest of oma-1;oma-2 mutant oocytes is suppressed by wee-1.3(RNAi), implying that progression through meiotic prophase I is critically dependent on inhibition of WEE-1.3 by either OMA-1 or OMA-2; OMA-1 is expressed primarily in maturing oocytes, is cytoplasmic and visible prior to cellularization. Paper_evidence: WBPaper00005198
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 19 Mar 2012 00:00:00
      Automated_description: Enables mRNA 3'-UTR AU-rich region binding activity and mRNA regulatory element binding translation repressor activity. Involved in several processes, including negative regulation of cell differentiation; oocyte development; and regulation of reproductive process. Located in P granule and centrosome. Part of messenger ribonucleoprotein complex. Expressed in several structures, including head muscle; neurons; oocyte; somatic nervous system; and vulva. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: EFO:MONDO:0014769 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1108)
  Molecular_info: Corresponding_CDS: C09G9.6
    Corresponding_transcript: C09G9.6.1
    Other_sequence: XIC01512_1
      HG11531
      XI03775
      SRC08713_1
      FC813056.1
    Associated_feature (15)
    Gene_product_binds: WBsf034245
    Transcription_factor: WBTranscriptionFactor000116
  Experimental_info: RNAi_result (29)
    Expr_pattern (16)
    Drives_construct (13)
    Construct_product (14)
    Antibody: WBAntibody00000486
      WBAntibody00000547
      WBAntibody00001073
      WBAntibody00001074
      WBAntibody00001087
      WBAntibody00001664
      WBAntibody00002447
    Microarray_results (20)
    Expression_cluster (207)
    Interaction (354)
    WBProcess: WBbiopr:00000068
      WBbiopr:00000073
  Map_info: Map: IV Position: 3.99916 Error: 0.001096
    Positive: Positive_clone: C09G9 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 7138
      Multi_point: 4054
        4056
        4064
        4065
  Reference: WBPaper00005198
    WBPaper00005454
    WBPaper00005930
    WBPaper00006085
    WBPaper00010630
    WBPaper00010668
    WBPaper00010802
    WBPaper00012537
    WBPaper00017837
    WBPaper00017838
    WBPaper00018617
    WBPaper00018755
    WBPaper00018768
    WBPaper00018887
    WBPaper00019036
    WBPaper00023917
    WBPaper00024312
    WBPaper00024507
    WBPaper00025650
    WBPaper00025747
    WBPaper00026080
    WBPaper00026378
    WBPaper00026516
    WBPaper00026970
    WBPaper00026975
    WBPaper00027080
    WBPaper00027224
    WBPaper00027238
    WBPaper00027298
    WBPaper00027309
    WBPaper00027310
    WBPaper00027320
    WBPaper00027607
    WBPaper00027739
    WBPaper00028423
    WBPaper00028730
    WBPaper00031129
    WBPaper00031702
    WBPaper00031842
    WBPaper00031867
    WBPaper00032146
    WBPaper00032265
    WBPaper00032287
    WBPaper00033085
    WBPaper00033447
    WBPaper00034932
    WBPaper00035436
    WBPaper00036019
    WBPaper00036909
    WBPaper00037129
    WBPaper00037685
    WBPaper00038491
    WBPaper00038621
    WBPaper00038735
    WBPaper00038743
    WBPaper00039209
    WBPaper00039584
    WBPaper00039588
    WBPaper00039589
    WBPaper00041400
    WBPaper00042062
    WBPaper00042959
    WBPaper00043308
    WBPaper00043745
    WBPaper00043747
    WBPaper00044147
    WBPaper00044760
    WBPaper00045802
    WBPaper00045803
    WBPaper00046178
    WBPaper00048493
    WBPaper00048539
    WBPaper00048543
    WBPaper00050819
    WBPaper00051310
    WBPaper00052021
    WBPaper00052136
    WBPaper00055090
    WBPaper00056632
    WBPaper00057125
    WBPaper00057140
    WBPaper00057808
    WBPaper00057881
    WBPaper00058597
    WBPaper00059332
    WBPaper00061125
    WBPaper00061137
    WBPaper00062120
    WBPaper00062457
    WBPaper00063103
    WBPaper00063533
    WBPaper00063960
    WBPaper00064664
    WBPaper00066192
  Picture: WBPicture0000013094
  Remark: Weak rescue of the zu405 embryonic lethality [Lin, R][021017 ck1]
    Sequence connection based on Lin, R [021017 ck1]
    Sequence connection from [Shimada M], [krb 020711]
    Postitive method is weak rescue of the zu405 embryonic lethality
  Method: Gene