WormBase Tree Display for Gene: WBGene00012364

WBGene00012364 SMap: S_parent: Sequence: W09D12
  Identity: Version: 2
    Name: CGC_name: zmp-4 Paper_evidence: WBPaper00036427
          Person_evidence: WBPerson345
      Sequence_name: W09D12.1
      Molecular_name: W09D12.1a
        W09D12.1a.1
        CE33197
        W09D12.1b
        CE52784
        W09D12.1b.1
      Other_name: CELE_W09D12.1 Accession_evidence: NDB BX284605
      Public_name: zmp-4
    DB_info: Database: AceView gene 5P398
        WormQTL gene WBGene00012364
        WormFlux gene WBGene00012364
        NDB locus_tag CELE_W09D12.1
        Panther gene CAEEL|WormBase=WBGene00012364|UniProtKB=Q23227
          family PTHR10201
        NCBI gene 179991
        RefSeq protein NM_001368476.2
            NM_074277.7
        TrEMBL UniProtAcc Q23227
            A0A3B1E3U1
        UniProt_GCRP UniProtAcc Q23227
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 04 Jan 2016 15:29:00 WBPerson2970 Name_change: CGC_name: zmp-4
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: zmp
    Allele (50)
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog: WBGene00061033 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00153096 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00130315 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00064350 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00051150 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00032707 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            WormBase-Compara
      WBGene00055542 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00151114 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00132799 Caenorhabditis japonica From_analysis: OMA
            WormBase-Compara
      WBGene00217686 Caenorhabditis japonica From_analysis: Inparanoid_8
      WBGene00190689 Caenorhabditis brenneri From_analysis: WormBase-Compara
      WBGene00226519 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g612 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g955 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g1208 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g6348 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g17777 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g1163 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g17713 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g17190 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g7910 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g23703 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00410.g10483 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-zmp-4 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g15877 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00325.g9434 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_16682 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_017414 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g02200 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g19739 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_50346100 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrV_pilon.g16645 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00247927 Onchocerca volvulus From_analysis: WormBase-Compara
      FB:FBgn0033438 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      ZFIN:ZDB-GENE-040426-2132 Danio rerio From_analysis: EnsEMBL-Compara
            Panther
      ZFIN:ZDB-GENE-050417-448 Danio rerio From_analysis: EnsEMBL-Compara
            Panther
      ZFIN:ZDB-GENE-030131-9548 Danio rerio From_analysis: EnsEMBL-Compara
            Panther
      HGNC:7166 Homo sapiens From_analysis: EnsEMBL-Compara
            Panther
      HGNC:7176 Homo sapiens From_analysis: EnsEMBL-Compara
            Panther
      HGNC:7171 Homo sapiens From_analysis: EnsEMBL-Compara
            Panther
      MGI:1347361 Mus musculus From_analysis: EnsEMBL-Compara
            Panther
      RGD:621316 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Panther
      RGD:621320 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Panther
      RGD:620201 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Panther
      RGD:1311376 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Panther
    Paralog: WBGene00006987 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00010423 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00010524 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012185 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016283 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00020646 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00019212 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00194737 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to be located in extracellular matrix. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and carcinoma (multiple). Is an ortholog of human MMP2 (matrix metallopeptidase 2); MMP23B (matrix metallopeptidase 23B); and MMP9 (matrix metallopeptidase 9). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (122)
  Molecular_info: Corresponding_CDS: W09D12.1a
      W09D12.1b
    Corresponding_CDS_history: W09D12.1:wp93
    Corresponding_transcript: W09D12.1a.1
      W09D12.1b.1
    Other_sequence: JI481101.1
      Hbac_isotig00330
      Oden_isotig17729
      CBC09438_1
      CJC10547_1
      FK799980.1
      Tcir_isotig15635
      EY473051.1
      Tcir_isotig15807
      OOC03931_1
      Tcol_isotig14136
      Acan_isotig05907
      Name_isotig01596
      Acan_isotig05906
      HBC00117_1
      Hbac_isotig00331
      FC553700.1
      ACC10665_1
      CBC12387_1
      EY464160.1
      FC543480.1
    Associated_feature: WBsf1002183
      WBsf1002184
      WBsf1020949
      WBsf235007
  Experimental_info: RNAi_result: WBRNAi00019748 Inferred_automatically: RNAi_primary
      WBRNAi00089182 Inferred_automatically: RNAi_primary
      WBRNAi00055040 Inferred_automatically: RNAi_primary
      WBRNAi00000622 Inferred_automatically: RNAi_primary
      WBRNAi00002142 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr14538
      Expr14539
      Expr1026445
      Expr1158579
      Expr2018181
      Expr2036318
    Drives_construct: WBCnstr00029982
      WBCnstr00040501
    Construct_product: WBCnstr00029982
      WBCnstr00040501
    Microarray_results (18)
    Expression_cluster (186)
    Interaction (258)
  Map_info: Map: V Position: 7.01111
    Positive: Positive_clone: W09D12 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00056095
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene