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WormBase Tree Display for Gene: WBGene00000411

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Name Class

WBGene00000411EvidenceCGC_data_submission
SMapS_parentSequenceR06F6
IdentityVersion1
NameCGC_namecdl-1Person_evidenceWBPerson634
Sequence_nameR06F6.1
Molecular_nameR06F6.1
R06F6.1.1
CE51537
Other_namehbp
CELE_R06F6.1Accession_evidenceNDBBX284602
Public_namecdl-1
DB_infoDatabaseAceViewgene2L75
WormQTLgeneWBGene00000411
WormFluxgeneWBGene00000411
NDBlocus_tagCELE_R06F6.1
PanthergeneCAEEL|WormBase=WBGene00000411|UniProtKB=Q09599
familyPTHR17408
NCBIgene174659
RefSeqproteinNM_063919.8
SwissProtUniProtAccQ09599
TREEFAMTREEFAM_IDTF316521
UniProt_GCRPUniProtAccQ09599
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcdl
Allele (37)
Legacy_information[A Sugimoto] Cell Death Lethal. w37: (null) zygotic lethal, embryonic arrest with accumulated cell corpses, body elongation defect, pharynx not connected to buccal cavity. e2501, e2510: (possibly neomorphs) similar to w37, but more severe corpse accumulation and elongation defect.
StrainWBStrain00022736
WBStrain00033878
WBStrain00036242
RNASeq_FPKM (74)
GO_annotation (16)
OrthologWBGene00053460Caenorhabditis remaneiFrom_analysisOMA
TreeFam
Inparanoid_8
WormBase-Compara
WBGene00025959Caenorhabditis briggsaeFrom_analysisHillier-set
OrthoMCL
OMA
Inparanoid_8
WormBase-Compara
WBGene00164434Caenorhabditis brenneriFrom_analysisOMA
TreeFam
Inparanoid_8
WormBase-Compara
WBGene00112926Pristionchus pacificusFrom_analysisOMA
Inparanoid_8
WormBase-Compara
WBGene00126278Caenorhabditis japonicaFrom_analysisOMA
TreeFam
Inparanoid_8
WormBase-Compara
WBGene00225515Brugia malayiFrom_analysisWormBase-Compara
CBOVI.g6950Caenorhabditis bovisFrom_analysisWormBase-Compara
CSP21.g9096Caenorhabditis parvicaudaFrom_analysisWormBase-Compara
CSP26.g1688Caenorhabditis zanzibariFrom_analysisWormBase-Compara
CSP28.g1172Caenorhabditis panamensisFrom_analysisWormBase-Compara
CSP29.g9141Caenorhabditis beceiFrom_analysisWormBase-Compara
CSP31.g16564Caenorhabditis uteleiaFrom_analysisWormBase-Compara
CSP32.g2435Caenorhabditis sulstoniFrom_analysisWormBase-Compara
CSP38.g7708Caenorhabditis quiockensisFrom_analysisWormBase-Compara
CSP39.g27686Caenorhabditis waitukubuliFrom_analysisWormBase-Compara
CSP40.g11552Caenorhabditis tribulationisFrom_analysisWormBase-Compara
Cang_2012_03_13_00305.g8885Caenorhabditis angariaFrom_analysisWormBase-Compara
Cni-cdl-1Caenorhabditis nigoniFrom_analysisWormBase-Compara
Csp11.Scaffold618.g6077Caenorhabditis tropicalisFrom_analysisWormBase-Compara
Csp5_scaffold_00036.g1977Caenorhabditis sinicaFrom_analysisWormBase-Compara
FL83_17670Caenorhabditis latensFrom_analysisWormBase-Compara
GCK72_005457Caenorhabditis remaneiFrom_analysisWormBase-Compara
Pan_g7637Panagrellus redivivusFrom_analysisWormBase-Compara
Sp34_20341710Caenorhabditis inopinataFrom_analysisWormBase-Compara
chrII_pilon.g5806Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00248261Onchocerca volvulusFrom_analysisWormBase-Compara
WBGene00257630Strongyloides rattiFrom_analysisWormBase-Compara
WBGene00259193Strongyloides rattiFrom_analysisWormBase-Compara
FB:FBgn0041186Drosophila melanogasterFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OrthoFinder
OrthoInspector
Panther
ZFIN:ZDB-GENE-030131-9686Danio rerioFrom_analysisEnsEMBL-Compara
Inparanoid
OrthoFinder
OrthoInspector
Panther
SonicParanoid
ZFIN:ZDB-GENE-070112-1722Danio rerioFrom_analysisEnsEMBL-Compara
OrthoFinder
OrthoInspector
Panther
SonicParanoid
HGNC:10904Homo sapiensFrom_analysisEnsEMBL-Compara
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
MGI:108402Mus musculusFrom_analysisEnsEMBL-Compara
Inparanoid
OrthoFinder
OrthoInspector
Panther
SonicParanoid
RGD:1584682Rattus norvegicusFrom_analysisEnsEMBL-Compara
Inparanoid
OrthoFinder
OrthoInspector
Panther
SonicParanoid
RGD:2323347Rattus norvegicusFrom_analysisEnsEMBL-Compara
OrthoFinder
OrthoInspector
Panther
Structured_descriptionConcise_descriptioncdl-1 encodes a homolog of human hairpin (stem-loop) binding proteins (HBP/SLBP) that bind to the hairpin (stem-loop) structure in the 3' untranslated region (3' UTR) of histone mRNAs, and thus promote histone pre-mRNA processing and translation of mature histone mRNA; CDL-1 is required for normally high levels of histone gene expression, normal cell division during late larval development, embryonic viability, normal vulval morphogenesis, normally rapid apoptosis, and fertility; CDL-1 binds to the stem-loop structure in the 3' UTR of core-histone mRNA; the cdl-1 promoter is most active in dividing cells during embryogenesis and postembryonic development; both CDL-1 and human HBP contain a minimal RNA-binding domain (RBD) of roughly 73 amino acids that has no similarity with other known RNA-binding motifs.Paper_evidenceWBPaper00004428
WBPaper00005085
WBPaper00005142
WBPaper00013577
Person_evidenceWBPerson1874
Curator_confirmedWBPerson13481
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables mRNA 3'-UTR binding activity. Involved in apoptotic process; embryo development; and mitotic chromosome condensation. Predicted to be located in cytoplasm. Predicted to be part of histone pre-mRNA 3'end processing complex. Expressed widely. Is an ortholog of human SLBP (stem-loop histone mRNA binding protein).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSR06F6.1
Corresponding_CDS_historyR06F6.1:wp252
Corresponding_transcriptR06F6.1.1
Other_sequenceAB060649
CSC01649_1
Dviv_isotig23248
ODC00101_1
AM157921.1
FC813592.1
Acan_isotig06403
FC819453.1
CBC00149_1
ACC11570_1
CGC00257_1
Oden_isotig19393
CR02278
FD515266.1
Tcir_isotig25725
SRC05739_1
EX562552.1
CRC00480_1
Associated_feature (12)
Experimental_infoRNAi_resultWBRNAi00082051Inferred_automaticallyRNAi_primary
WBRNAi00069364Inferred_automaticallyRNAi_primary
WBRNAi00009038Inferred_automaticallyRNAi_primary
WBRNAi00008237Inferred_automaticallyRNAi_primary
WBRNAi00034665Inferred_automaticallyRNAi_primary
WBRNAi00051393Inferred_automaticallyRNAi_primary
WBRNAi00026046Inferred_automaticallyRNAi_primary
WBRNAi00069365Inferred_automaticallyRNAi_primary
WBRNAi00082056Inferred_automaticallyRNAi_primary
WBRNAi00086822Inferred_automaticallyRNAi_primary
Expr_patternExpr1840
Expr10540
Expr1028207
Expr1030228
Expr1155082
Expr2009819
Expr2028060
Drives_constructWBCnstr00010480
WBCnstr00015525
WBCnstr00037562
Construct_productWBCnstr00015525
WBCnstr00037562
Microarray_results (21)
Expression_cluster (193)
Interaction (122)
WBProcessWBbiopr:00000014
WBbiopr:00000015
WBbiopr:00000036
WBbiopr:00000098
Map_infoMapIIPosition3.12577Error0.000223
Well_ordered
PositivePositive_cloneR06F6Inferred_automaticallyFrom sequence, transcript, pseudogene data
T19E10Person_evidenceWBPerson634
Mapping_dataMulti_point4880
Pos_neg_data10583
10584
10585
10586
Reference (22)
MethodGene