WormBase Tree Display for Gene: WBGene00004347
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| WBGene00004347 | SMap | S_parent | Sequence | Y38E10A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | rgs-4 | Person_evidence | WBPerson330 | |||||
| Sequence_name | Y38E10A.21 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | CELE_Y38E10A.21 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | rgs-4 | ||||||||
| DB_info | Database | AceView | gene | 2M957 | |||||
| WormQTL | gene | WBGene00004347 | |||||||
| WormFlux | gene | WBGene00004347 | |||||||
| NDB | locus_tag | CELE_Y38E10A.21 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004347|UniProtKB=H2KMK7 | |||||||
| family | PTHR10845 | ||||||||
| NCBI | gene | 189666 | |||||||
| RefSeq | protein | NM_001381631.1 | |||||||
| NM_001377886.2 | |||||||||
| NM_001267421.4 | |||||||||
| NM_001373807.2 | |||||||||
| TrEMBL | UniProtAcc | H2KMK5 | |||||||
| A0A5S9MNH1 | |||||||||
| A0A486WXG8 | |||||||||
| H2KMK7 | |||||||||
| UniProt_GCRP | UniProtAcc | A0A5S9MNH1 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:35 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 03 Dec 2004 16:28:54 | WBPerson2970 | Event | Acquires_merge | WBGene00012599 | ||||
| 3 | 21 Nov 2019 16:12:41 | WBPerson4025 | Event | Acquires_merge | WBGene00012598 | ||||
| Acquires_merge | WBGene00012599 | ||||||||
| WBGene00012598 | |||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rgs | ||||||||
| Allele (540) | |||||||||
| Strain | WBStrain00026366 | ||||||||
| WBStrain00031678 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| Ortholog (31) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | rgs-4 encodes a regulator of G protein signaling; by homology, RGS-4 is predicted to function as a GTPase-activating protein that binds G protein alpha subunits and negatively regulates heterotrimeric G protein signaling; loss of rgs-4 activity via RNAi or a deletion mutation results in no obvious defects, and likewise, rgs-4 overexpression has no measurable effect on egg-laying behavior, locomotion, or viability; the RGS-4 expression pattern has not yet been reported. | Paper_evidence | WBPaper00004281 | |||||
| WBPaper00024480 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 07 Feb 2005 00:00:00 | ||||||||
| Automated_description | Enriched in head mesodermal cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; glp-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: RGS domain; RGS domain superfamily; Regulator of G protein signaling domain; and RGS, subdomain 2. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y38E10A.21a | |||||||
| Y38E10A.21b | |||||||||
| Y38E10A.21c | |||||||||
| Y38E10A.21d | |||||||||
| Corresponding_CDS_history | Y38E10A.21:wp229 | ||||||||
| Y38E10A.21a:wp274 | |||||||||
| Corresponding_transcript | Y38E10A.21a.1 | ||||||||
| Y38E10A.21b.1 | |||||||||
| Y38E10A.21c.1 | |||||||||
| Y38E10A.21d.1 | |||||||||
| Other_sequence (36) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00020288 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00056020 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00020287 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00056021 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (10) | |||||||||
| Drives_construct | WBCnstr00004337 | ||||||||
| Microarray_results | SMD_Y38E10A.U | ||||||||
| SMD_Y38E10A.V | |||||||||
| 187038_at | |||||||||
| 187115_at | |||||||||
| A_12_P103351 | |||||||||
| A_12_P111440 | |||||||||
| GPL13394_WBGene00004347 | |||||||||
| GPL13394_WBGene00012598 | |||||||||
| GPL13914_Y38E10A.20 | |||||||||
| GPL13914_Y38E10A.21 | |||||||||
| GPL14144_Y38E10A.20_143-202_0.742_29_C | |||||||||
| GPL14144_Y38E10A.20_258-317_0.923_1_A | |||||||||
| GPL14144_Y38E10A.20_34-93_0.920_3_B | |||||||||
| GPL14144_Y38E10A.21_405-464_0.942_3_B | |||||||||
| GPL14144_Y38E10A.21_505-564_0.935_6_C | |||||||||
| GPL14144_Y38E10A.21_598-657_0.964_1_A | |||||||||
| GPL19516_CGZ0044573 | |||||||||
| GPL19516_CGZ0044574 | |||||||||
| GPL19516_CGZ0044575 | |||||||||
| GPL21109_Y38E10A.20 | |||||||||
| GPL21109_Y38E10A.21a | |||||||||
| GPL3518_CE21601 | |||||||||
| GPL3518_CE21602 | |||||||||
| GPL8304_CE_WBGene00004347_A | |||||||||
| GPL8304_CE_WBGene00004347_B | |||||||||
| GPL8304_CE_WBGene00012598_A | |||||||||
| GPL8673_Y38E10A_20P00213 | |||||||||
| GPL8673_Y38E10A_20P00246 | |||||||||
| GPL8673_Y38E10A_20P00483 | |||||||||
| GPL8673_Y38E10A_21P00450 | |||||||||
| GPL8673_Y38E10A_21P00646 | |||||||||
| GPL9450_Y38E10A.20 | |||||||||
| GPL9450_Y38E10A.21 | |||||||||
| cea2.i.16699 | |||||||||
| cea2.i.16709 | |||||||||
| Expression_cluster (131) | |||||||||
| Map_info | Map | II | Position | 10.6551 | Error | 0.037636 | |||
| Positive | Positive_clone | Y38E10A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4624 | |||||||
| 4673 | |||||||||
| 5028 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00004281 | ||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
