WormBase Tree Display for Gene: WBGene00004008
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WBGene00004008 | SMap | S_parent | Sequence | F22E10 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | pgp-14 | Person_evidence | WBPerson490 | |||||
Sequence_name | F22E10.3 | ||||||||
Molecular_name | F22E10.3 | ||||||||
F22E10.3.1 | |||||||||
CE03262 | |||||||||
Other_name | CELE_F22E10.3 | Accession_evidence | NDB | BX284606 | |||||
Public_name | pgp-14 | ||||||||
DB_info | Database | AceView | gene | XN364 | |||||
WormQTL | gene | WBGene00004008 | |||||||
WormFlux | gene | WBGene00004008 | |||||||
NDB | locus_tag | CELE_F22E10.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00004008|UniProtKB=G5EG61 | |||||||
family | PTHR24221 | ||||||||
NCBI | gene | 181416 | |||||||
RefSeq | protein | NM_077727.10 | |||||||
TrEMBL | UniProtAcc | G5EG61 | |||||||
UniProt_GCRP | UniProtAcc | G5EG61 | |||||||
OMIM | gene | 171050 | |||||||
171060 | |||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | pgp | ||||||||
Allele (62) | |||||||||
Strain | WBStrain00001996 | ||||||||
WBStrain00032692 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (13) | |||||||||
Contained_in_operon | CEOPX110 | ||||||||
Ortholog (53) | |||||||||
Paralog (24) | |||||||||
Structured_description | Concise_description | pgp-14 encodes a member of the ABC transporter family with high similarity to the vertebrate MDR (multidrug resistance) family; PGP-14 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-14 activity via large-scale RNAi screens does not result in any obvious defects, the precise role of pgp-14 in C. elegans development and/or behavior is not yet known; pgp-14 promoter-gfp fusion proteins are expressed in larvae and adults in the anterior pharynx. | Paper_evidence | WBPaper00006421 | |||||
WBPaper00006525 | |||||||||
WBPaper00024561 | |||||||||
Curator_confirmed | WBPerson48 | ||||||||
WBPerson1843 | |||||||||
Date_last_updated | 07 Mar 2006 00:00:00 | ||||||||
Automated_description | Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in response to nematicide. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human ABCB1 (ATP binding cassette subfamily B member 1); ABCB4 (ATP binding cassette subfamily B member 4); and ABCB5 (ATP binding cassette subfamily B member 5). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model (39) | ||||||||
Molecular_info | Corresponding_CDS | F22E10.3 | |||||||
Corresponding_transcript | F22E10.3.1 | ||||||||
Other_sequence | JI168113.1 | ||||||||
JI235600.1 | |||||||||
JI231282.1 | |||||||||
JI164894.1 | |||||||||
Acan_isotig21429 | |||||||||
JI218053.1 | |||||||||
CJC02657_1 | |||||||||
ASC19568_1 | |||||||||
JI241304.1 | |||||||||
Associated_feature | WBsf238081 | ||||||||
WBsf238082 | |||||||||
WBsf238083 | |||||||||
Experimental_info | RNAi_result | WBRNAi00045324 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00000347 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00077361 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00013753 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr3326 | ||||||||
Expr3327 | |||||||||
Expr4618 | |||||||||
Expr5828 | |||||||||
Expr1031917 | |||||||||
Expr1149248 | |||||||||
Expr2014867 | |||||||||
Expr2033102 | |||||||||
Drives_construct | WBCnstr00002780 | ||||||||
WBCnstr00011322 | |||||||||
WBCnstr00011323 | |||||||||
WBCnstr00012122 | |||||||||
WBCnstr00035743 | |||||||||
Construct_product | WBCnstr00035743 | ||||||||
Microarray_results | SMD_F22E10.3 | ||||||||
173817_at | |||||||||
190248_s_at | |||||||||
A_12_P104950 | |||||||||
Aff_F22E10.3 | |||||||||
GPL13394_WBGene00004008 | |||||||||
GPL13914_F22E10.3 | |||||||||
GPL19516_CGZ0017530 | |||||||||
GPL21109_F22E10.3 | |||||||||
GPL3518_CE03262 | |||||||||
GPL8304_CE_WBGene00004008_A | |||||||||
GPL8673_F22E10_3P02607 | |||||||||
GPL8673_F22E10_3P03521 | |||||||||
GPL8673_F22E10_3P03873 | |||||||||
GPL9450_F22E10.3 | |||||||||
cea2.p.142091 | |||||||||
Expression_cluster (235) | |||||||||
Interaction (33) | |||||||||
Map_info | Map | X | Position | 8.21375 | Error | 0.008856 | |||
Positive | Positive_clone | F22E10 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference (12) | |||||||||
Remark | Sequence connection from [Sheps JA, Baillie DL] [040902 ck1] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |