WormBase Tree Display for Gene: WBGene00001397

WBGene00001397 SMap: S_parent: Sequence: W06D12
  Identity: Version: 1
    Name: CGC_name: fat-5
      Sequence_name: W06D12.3
      Molecular_name: W06D12.3
        W06D12.3.1
        CE16551
      Other_name: CELE_W06D12.3 Accession_evidence: NDB BX284605
      Public_name: fat-5
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fat
    Allele (67)
    Strain: WBStrain00004015
      WBStrain00004016
      WBStrain00004022
      WBStrain00008408
      WBStrain00008411
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (59)
    Paralog: WBGene00001399 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00001398 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: fat-5 encodes a delta-9 fatty acid desaturase that is predicted to be mitochondrial; when expressed heterologously in S. cerevisiae, FAT-5 rescues the fatty acid auxotrophy of the yeast delta-9 desaturase mutant ole1. Paper_evidence: WBPaper00004149
            WBPaper00004424
            WBPaper00013538
            WBPaper00013550
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable iron ion binding activity and stearoyl-CoA 9-desaturase activity. Involved in long-chain fatty acid biosynthetic process and post-embryonic development. Predicted to be located in endoplasmic reticulum membrane. Expressed in intestine and tail. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 79. Is an ortholog of human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0112160 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:21088)
  Molecular_info: Corresponding_CDS: W06D12.3
    Corresponding_transcript: W06D12.3.1
    Other_sequence (39)
    Associated_feature: WBsf662183
      WBsf717286
      WBsf1002730
      WBsf1021337
  Experimental_info: RNAi_result (16)
    Expr_pattern: Expr4290
      Expr4572
      Expr13449
      Expr1020843
      Expr1158423
      Expr2011438
      Expr2029676
    Drives_construct: WBCnstr00011888
    Construct_product: WBCnstr00011888
      WBCnstr00016673
    Microarray_results (22)
    Expression_cluster (352)
    Interaction: WBInteraction000005769
      WBInteraction000005770
      WBInteraction000008929
      WBInteraction000008979
      WBInteraction000008985
      WBInteraction000009019
      WBInteraction000009021
      WBInteraction000009023
      WBInteraction000009025
      WBInteraction000044249
      WBInteraction000050453
      WBInteraction000050454
      WBInteraction000050455
      WBInteraction000050456
      WBInteraction000052708
      WBInteraction000134002
      WBInteraction000134003
      WBInteraction000163881
      WBInteraction000163882
      WBInteraction000176441
      WBInteraction000191912
      WBInteraction000198106
      WBInteraction000206692
      WBInteraction000273587
      WBInteraction000283487
      WBInteraction000298239
      WBInteraction000306648
      WBInteraction000314706
      WBInteraction000321068
      WBInteraction000339399
      WBInteraction000356951
      WBInteraction000362206
      WBInteraction000366402
      WBInteraction000381346
      WBInteraction000383637
      WBInteraction000388956
      WBInteraction000405643
      WBInteraction000408156
      WBInteraction000409775
      WBInteraction000412557
      WBInteraction000413000
      WBInteraction000414481
      WBInteraction000429410
      WBInteraction000432679
      WBInteraction000436618
      WBInteraction000450682
      WBInteraction000453522
      WBInteraction000457598
      WBInteraction000458674
      WBInteraction000462725
      WBInteraction000464052
      WBInteraction000465869
      WBInteraction000466090
      WBInteraction000468140
      WBInteraction000468835
      WBInteraction000469080
      WBInteraction000469355
      WBInteraction000471064
      WBInteraction000471084
      WBInteraction000471085
      WBInteraction000471086
      WBInteraction000471087
      WBInteraction000471197
      WBInteraction000471284
      WBInteraction000471822
      WBInteraction000472155
      WBInteraction000472253
      WBInteraction000472254
      WBInteraction000472355
      WBInteraction000472502
      WBInteraction000472898
      WBInteraction000473148
      WBInteraction000473389
      WBInteraction000474439
      WBInteraction000475426
      WBInteraction000502084
      WBInteraction000502412
      WBInteraction000502844
      WBInteraction000504149
      WBInteraction000504207
      WBInteraction000504921
      WBInteraction000505325
      WBInteraction000505326
      WBInteraction000505327
      WBInteraction000505328
      WBInteraction000505329
      WBInteraction000517800
      WBInteraction000525145
      WBInteraction000534867
      WBInteraction000535445
      WBInteraction000540546
      WBInteraction000540609
      WBInteraction000542319
      WBInteraction000542320
      WBInteraction000542321
      WBInteraction000549515
      WBInteraction000549516
      WBInteraction000549518
      WBInteraction000556298
      WBInteraction000556299
      WBInteraction000558852
      WBInteraction000563881
      WBInteraction000571061
      WBInteraction000573255
      WBInteraction000573261
      WBInteraction000579995
      WBInteraction000585594
  Map_info: Map: V Position: 13.0767 Error: 0.008308
    Positive: Positive_clone: W06D12 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4301
        5388
        5600
        5656
    Pseudo_map_position
  Reference: WBPaper00004149
    WBPaper00018784
    WBPaper00024086
    WBPaper00024111
    WBPaper00025114
    WBPaper00026097
    WBPaper00026349
    WBPaper00026800
    WBPaper00027288
    WBPaper00027365
    WBPaper00027683
    WBPaper00027749
    WBPaper00029195
    WBPaper00029292
    WBPaper00031095
    WBPaper00031804
    WBPaper00032232
    WBPaper00032563
    WBPaper00033126
    WBPaper00033136
    WBPaper00033382
    WBPaper00033801
    WBPaper00034504
    WBPaper00035503
    WBPaper00037502
    WBPaper00038223
    WBPaper00038491
    WBPaper00038982
    WBPaper00040208
    WBPaper00040386
    WBPaper00040706
    WBPaper00040998
    WBPaper00041881
    WBPaper00042178
    WBPaper00042257
    WBPaper00042964
    WBPaper00043167
    WBPaper00044578
    WBPaper00044659
    WBPaper00048987
    WBPaper00052845
    WBPaper00053178
    WBPaper00053328
    WBPaper00053474
    WBPaper00055057
    WBPaper00055090
    WBPaper00055256
    WBPaper00056739
    WBPaper00056969
    WBPaper00059111
    WBPaper00059191
    WBPaper00059378
    WBPaper00059578
    WBPaper00059658
    WBPaper00059722
    WBPaper00059995
    WBPaper00060060
    WBPaper00060264
    WBPaper00060893
    WBPaper00061746
    WBPaper00062149
    WBPaper00062322
    WBPaper00062492
    WBPaper00062625
    WBPaper00062858
    WBPaper00063942
    WBPaper00064105
    WBPaper00064284
    WBPaper00064370
    WBPaper00064505
    WBPaper00064516
    WBPaper00064592
    WBPaper00064634
    WBPaper00064721
    WBPaper00064731
    WBPaper00064820
    WBPaper00064979
    WBPaper00065081
    WBPaper00065123
    WBPaper00065133
    WBPaper00065695
    WBPaper00065727
    WBPaper00065859
    WBPaper00065904
    WBPaper00065942
    WBPaper00065988
    WBPaper00066260
    WBPaper00066295
  Picture: WBPicture0000013088
    WBPicture0000013098
  Remark: sequence connection from [Watts J]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene