WormBase Tree Display for Gene: WBGene00006785
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WBGene00006785 | SMap | S_parent | Sequence | T07A5 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name (5) | |||||||
DB_info | Database | AceView | gene | 3L404 | |||
WormQTL | gene | WBGene00006785 | |||||
WormFlux | gene | WBGene00006785 | |||||
NDB | locus_tag | CELE_T07A5.2 | |||||
Panther | gene | CAEEL|WormBase=WBGene00006785|UniProtKB=Q10045 | |||||
family | PTHR12841 | ||||||
NCBI | gene | 176443 | |||||
RefSeq | protein | NM_066878.5 | |||||
SwissProt | UniProtAcc | Q10045 | |||||
TREEFAM | TREEFAM_ID | TF105624 | |||||
UniProt_GCRP | UniProtAcc | Q10045 | |||||
Species | Caenorhabditis elegans | ||||||
History (2) | |||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | unc | ||||||
Reference_allele | WBVar00143101 | ||||||
Allele (57) | |||||||
Legacy_information | e306 : weak kinker slow but fairly active resistant to 1 mM levamisole sensitive to hypoosmotic shock. ES3 ME1. NA7 (e425 etc. : all similar to e306). | ||||||
[C.elegansII] e306 : weak kinker, slow but fairly active; resistant to 1 mM levamisole sensitive to hypoosmotic shock. Extracts lack levamisole binding. ES3 ME1. OA6: e425 etc. (all similar). Cloned: encodes predicted 301 aa novel protein, possible TM domain. [Lewis et al. 1980; MT; WS; ZZ] | |||||||
Strain | WBStrain00027163 | ||||||
WBStrain00027198 | |||||||
WBStrain00027199 | |||||||
WBStrain00032235 | |||||||
WBStrain00004144 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00056029 | ||||||
00056030 | |||||||
00056031 | |||||||
00056032 | |||||||
00056033 | |||||||
00056034 | |||||||
00056035 | |||||||
00056036 | |||||||
Contained_in_operon | CEOP3832 | ||||||
Ortholog (35) | |||||||
Structured_description | Concise_description | unc-50 encodes an integral membrane protein orthologous to the Saccharomyces cerevisiae Golgi component Gmh1p; UNC-50 is required for regulating subtype-specific ionotropic acetylcholine receptor trafficking to the cell surface and thus, for normal synaptic transmission at the neuromuscular junction; UNC-50 is ubiquitously expressed from early embryogenesis to adulthood and localizes to the Golgi. | Paper_evidence | WBPaper00031010 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 29 Jul 2015 00:00:00 | ||||||
Automated_description | Involved in receptor localization to synapse and regulation of muscle contraction. Located in Golgi membrane. Expressed in several structures, including alimentary muscle; gonad; intestine; neurons; and vulval muscle. Is an ortholog of human UNC50 (unc-50 inner nuclear membrane RNA binding protein). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | T07A5.2 | |||||
Corresponding_transcript | T07A5.2.1 | ||||||
Other_sequence (51) | |||||||
Associated_feature | WBsf227435 | ||||||
WBsf227436 | |||||||
Experimental_info | RNAi_result (13) | ||||||
Expr_pattern | Expr4027 | ||||||
Expr4910 | |||||||
Expr4911 | |||||||
Expr1012237 | |||||||
Expr1032856 | |||||||
Expr1156300 | |||||||
Expr2017883 | |||||||
Expr2036019 | |||||||
Drives_construct | WBCnstr00012326 | ||||||
WBCnstr00034152 | |||||||
Construct_product | WBCnstr00012325 | ||||||
WBCnstr00034152 | |||||||
Microarray_results (23) | |||||||
Expression_cluster (106) | |||||||
Interaction (17) | |||||||
Map_info | Map | III | Position | 2.30916 | Error | 0.004481 | |
Well_ordered | |||||||
Positive | Inside_rearr | nDp2 | |||||
Positive_clone | T07A5 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
Mapping_data | 2_point | 56 | |||||
75 | |||||||
Multi_point (27) | |||||||
Pos_neg_data | 650 | ||||||
1619 | |||||||
2722 | |||||||
3243 | |||||||
5726 | |||||||
5734 | |||||||
804 | |||||||
1629 | |||||||
Landmark_gene | |||||||
Reference (54) | |||||||
Remark | on same cosmid as unc-69; genetic map data indicate unc-69 left of unc-50 JAH 01/01 | ||||||
Method | Gene |