WormBase Tree Display for Gene: WBGene00006590

WBGene00006590 SMap: S_parent: Sequence: ZC395
  Identity: Version: 1
    Name: CGC_name: toc-1 Person_evidence: WBPerson247
      Sequence_name: ZC395.3
      Molecular_name: ZC395.3a
        ZC395.3a.1
        CE15207
        ZC395.3b
        CE01439
        ZC395.3a.2
        ZC395.3b.1
      Other_name: CELE_ZC395.3 Accession_evidence: NDB BX284603
      Public_name: toc-1
    DB_info: Database: WormQTL gene WBGene00006590
        WormFlux gene WBGene00006590
        NDB locus_tag CELE_ZC395.3
        Panther gene CAEEL|WormBase=WBGene00006590|UniProtKB=Q45EL5
          family PTHR46531
        NCBI gene 175728
        RefSeq protein NM_001379701.1
            NM_001392094.1
        TREEFAM TREEFAM_ID TF313167
        TrEMBL UniProtAcc Q23281
            Q45EL5
        UniProt_GCRP UniProtAcc Q45EL5
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:41 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: toc
    Allele (35)
    Legacy_information: [Ewbank JJ] toc for similarity to Transporter Of divalent Cations (transporter in operon with clk-1). Predicted gene ZC395.3, SL1 trans-spliced, upstream of clk-1 (ZC395.2)
    Strain: WBStrain00001184
    RNASeq_FPKM (74)
    GO_annotation (12)
    Contained_in_operon: CEOP3280
    Ortholog (32)
    Paralog: WBGene00000393 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00010644 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00011821 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00012712 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00013668 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00018948 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00019803 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00019841 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00044481 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: toc-1 encodes an integral membrane protein with similarity to divalent metal ion transporters; by homology, TOC-1 is predicted to function in regulation of intracellular metal ion (particularly zinc) homeostasis; toc-1 is the upstream gene in an operon with clk-1, a timing gene that is necessary for ubiquinone biosynthesis; RNAi experiments directed against toc-1 sequences result in egg-laying defects, abnormal body coloration, retarded postembryonic growth rates, and generally sick animals. Paper_evidence: WBPaper00002658
            WBPaper00004651
            WBPaper00005654
            WBPaper00006395
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable monoatomic cation transmembrane transporter activity. Predicted to be involved in zinc ion transport. Predicted to be located in Golgi apparatus. Is an ortholog of human SLC30A6 (solute carrier family 30 member 6). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZC395.3a
      ZC395.3b
    Corresponding_CDS_history: ZC395.3:wp146
    Corresponding_transcript: ZC395.3a.1
      ZC395.3a.2
      ZC395.3b.1
    Other_sequence (32)
    Associated_feature (11)
  Experimental_info: RNAi_result: WBRNAi00005100 Inferred_automatically: RNAi_primary
      WBRNAi00038033 Inferred_automatically: RNAi_primary
      WBRNAi00061700 Inferred_automatically: RNAi_primary
      WBRNAi00027011 Inferred_automatically: RNAi_primary
      WBRNAi00009439 Inferred_automatically: RNAi_primary
      WBRNAi00108004 Inferred_automatically: RNAi_primary
      WBRNAi00058869 Inferred_automatically: RNAi_primary
      WBRNAi00107999 Inferred_automatically: RNAi_primary
      WBRNAi00000897 Inferred_automatically: RNAi_primary
      WBRNAi00067872 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1675
      Expr7166
      Expr1011036
      Expr1032723
      Expr1162309
      Expr2017438
      Expr2035577
    Drives_construct: WBCnstr00002076
    Construct_product: WBCnstr00040348
    Microarray_results (25)
    Expression_cluster (105)
    Interaction: WBInteraction000007326
      WBInteraction000207347
      WBInteraction000257526
      WBInteraction000316087
      WBInteraction000353734
      WBInteraction000426025
      WBInteraction000438960
      WBInteraction000554721
      WBInteraction000574309
  Map_info: Map: III Position: -1.84873 Error: 0.000552
    Positive: Positive_clone: ZC395 Person_evidence: WBPerson168
          Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00002658
    WBPaper00015440
    WBPaper00038491
    WBPaper00048663
    WBPaper00055090
  Remark: Data extracted from Ewbank et al. (1997)
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene